Acanthamoeba Keratitis in Minors With Orthokeratology (OK) Lens Use: A Case Series.


Journal

Eye & contact lens
ISSN: 1542-233X
Titre abrégé: Eye Contact Lens
Pays: United States
ID NLM: 101160941

Informations de publication

Date de publication:
01 Feb 2021
Historique:
accepted: 29 05 2020
pubmed: 11 7 2020
medline: 19 8 2021
entrez: 11 7 2020
Statut: ppublish

Résumé

Myopia progression is a significant public health issue. Methods to halt myopia progression in minors continue to gain momentum. Orthokeratology, with market penetrance estimates approximating 1%, is a corneal reshaping therapy and potential myopia progression treatment. Our objective was to explore whether orthokeratology may increase the frequency of Acanthamoeba keratitis compared with other lens modalities. Individuals less than 18 years diagnosed with Acanthamoeba keratitis (AK) at the University of Illinois at Chicago (UIC) Cornea Service between January 1st, 2003, and December 31st, 2016, were retrospectively reviewed. Subjects were grouped by lens modality (soft, rigid gas permeable [RGP], and orthokeratology), and all cases with orthokeratology lens use were reviewed. The primary outcome was a history of orthokeratology lens use in minors diagnosed with AK. Forty-seven contact lens users less than 18 years were diagnosed with AK. The mean age was 15.0 years (range 12-17), 26 (55%) were women, and 4 (8.5%) had bilateral disease. Lens modality included 6 (13%) with orthokeratology, 39 (83%) with soft contact lenses, 0 with nonorthokeratology RGP (0%), and 2 (4%) unknown. The proportion of orthokeratology cases among AK minors (13%) in our case series exceeds the expected proportion of orthokeratology cases expected based on orthokeratology market penetrance (1%). Results from this case series suggest a potential increased risk of AK in orthokeratology users compared with other lens modalities. In the context of the current myopia epidemic and concerns for halting myopia progression in minors, caution should be exercised when selecting appropriate treatment options to minimize the risk of AK.

Identifiants

pubmed: 32649389
pii: 00140068-202102000-00002
doi: 10.1097/ICL.0000000000000728
pmc: PMC7790837
mid: NIHMS1600168
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

71-73

Subventions

Organisme : NEI NIH HHS
ID : K12 EY021475
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY001792
Pays : United States

Informations de copyright

Copyright © 2020 Contact Lens Association of Ophthalmologists.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to disclose.

Références

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Auteurs

Angelica C Scanzera (AC)

Department of Ophthalmology and Visual Sciences (A.C.S., E.Y.T., C.E.J.), University of Illinois at Chicago, Chicago, IL; and Division of Epidemiology and Biostatistics (A.C.S., C.E.J.), School of Public Health, University of Illinois at Chicago, Chicago, IL.

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