Sex-Specific Outcomes in Patients with Acute Coronary Syndrome.
Germany
ST-elevation myocardial infarction (STEMI)
acute coronary syndrome
inhospital mortality
myocardial infarction
non-STEMI (NSTEMI)
outcome
sex
trend
unstable angina pectoris
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
06 Jul 2020
06 Jul 2020
Historique:
received:
11
06
2020
revised:
24
06
2020
accepted:
28
06
2020
entrez:
10
7
2020
pubmed:
10
7
2020
medline:
10
7
2020
Statut:
epublish
Résumé
Sex differences in patients with acute coronary syndrome (ACS) are a matter of debate. We investigated sex-specific differences in the incidence, outcomes, and related interventions in patients diagnosed with ACS in Germany over the past decade. All ACS cases from 2005 to 2015 were collected. Procedures and inhospital mortality were assessed by sex. Age-adjusted incidence rates were calculated. In total, 1,366,045 females and 2,431,501 males presenting with ACS were recorded. Females were older than males (73.1 vs. 66.4 years of age), had a longer mean hospital stay (7.7 vs. 6.9 days), and less frequently underwent coronary angiographies (55% vs. 66%) and coronary interventions (35% vs. 47%). The age-adjusted incidence rate of ACS was lower in females than in males, and decreased in both sexes from 2005 to 2015. The age-adjusted inhospital mortality rate was substantially higher in females than in males, but decreased in both sexes over time (in females, from 87 to 71 cases per 1000 person years; in males, from 57 to 51 cases per 1000 person years). In conclusion, we reported sex differences in the incidence, treatment, and outcomes of ACS patients in Germany within the past decade. Women had a substantially higher mortality rate and lower rate of coronary interventions.
Identifiants
pubmed: 32640661
pii: jcm9072124
doi: 10.3390/jcm9072124
pmc: PMC7408894
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Deutsche Forschungsgesellschaft
ID : NE 2165/1-1
Références
JAMA. 2009 Aug 26;302(8):874-82
pubmed: 19706861
Eur Heart J Acute Cardiovasc Care. 2016 Aug;5(4):347-53
pubmed: 25954017
J Am Coll Cardiol. 2015 Jun 16;65(23):2496-507
pubmed: 26065988
JAMA. 2012 Feb 22;307(8):813-22
pubmed: 22357832
Cardiol Clin. 2005 Nov;23(4):411-21, v
pubmed: 16278115
EuroIntervention. 2016 Aug 05;12(5):e542-9
pubmed: 27497354
Circ Cardiovasc Qual Outcomes. 2017 Dec;10(12):e003443
pubmed: 29246884
Arch Intern Med. 2009 Oct 26;169(19):1767-74
pubmed: 19858434
Catheter Cardiovasc Interv. 2015 Aug;86(2):E58-65
pubmed: 25810163
JAMA. 2005 Nov 23;294(20):2623-9
pubmed: 16304077
Nat Rev Cardiol. 2017 Aug;14(8):472-483
pubmed: 28383022
Eur Heart J. 2011 Dec;32(24):3107-14
pubmed: 21920968
Eur Heart J. 2011 Dec;32(24):3128-36
pubmed: 21911338
N Engl J Med. 2012 Jan 5;366(1):54-63
pubmed: 22216842
Eur Heart J. 2012 Mar;33(5):630-9
pubmed: 22009446
Heart Lung Circ. 2017 Dec;26(12):1282-1290
pubmed: 28262338
Natl Health Stat Report. 2010 Aug 6;(26):1-31
pubmed: 20726217
JAMA Netw Open. 2019 Mar 1;2(3):e191938
pubmed: 30874787
N Engl J Med. 1999 Jul 22;341(4):226-32
pubmed: 10413734
N Engl J Med. 1999 Jul 22;341(4):217-25
pubmed: 10413733
J Am Heart Assoc. 2018 Mar 10;7(6):
pubmed: 29525782
J Am Coll Cardiol. 2015 Nov 3;66(18):1961-1972
pubmed: 26515998
N Engl J Med. 2019 Jun 27;380(26):2529-2540
pubmed: 31242362
JAMA. 2012 Sep 12;308(10):998-1006
pubmed: 22928184
Circulation. 2007 Mar 6;115(9):1067-74
pubmed: 17339564
Chest. 2004 Aug;126(2):461-9
pubmed: 15302732
Arch Cardiovasc Dis. 2014 May;107(5):291-8
pubmed: 24910083
N Engl J Med. 2010 Jun 10;362(23):2155-65
pubmed: 20558366
Eur Heart J. 2016 Apr 21;37(16):1304-11
pubmed: 26757786
J Am Coll Cardiol. 2019 Dec 17;74(24):3013-3022
pubmed: 31865968
Eur Heart J. 2018 Nov 7;39(42):3766-3776
pubmed: 30239671
JAMA. 2007 May 2;297(17):1892-900
pubmed: 17473299
JAMA Intern Med. 2014 Feb 1;174(2):241-9
pubmed: 24275751
Lancet. 2004 Sep 11-17;364(9438):937-52
pubmed: 15364185
Clin Res Cardiol. 2015 Aug;104(8):648-55
pubmed: 25687366
Int J Cardiol. 2013 Sep 30;168(2):1041-7
pubmed: 23168004
J Am Heart Assoc. 2017 Mar 20;6(3):
pubmed: 28320749
Eur Heart J. 2017 Apr 7;38(14):1060-1065
pubmed: 28329052