Long-term efficacy of immunoglobulins in small fiber neuropathy related to Sjögren's syndrome.
Small fiber sensory neuropathies and sjögren syndrome
Small fiber sensory neuropathies and sjögren syndrome and treatment
Small fiber sensory neuropathies in sjögren syndrome and immunoglobulins
Small fiber sensory neuropathies in sjögren syndrome and intravenous immunoglobulins
Small fiber sensory neuropathies in sjögren syndrome and subcutaneous immunoglobulins
Journal
Journal of neurology
ISSN: 1432-1459
Titre abrégé: J Neurol
Pays: Germany
ID NLM: 0423161
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
14
05
2020
accepted:
26
06
2020
revised:
24
06
2020
pubmed:
3
7
2020
medline:
22
6
2021
entrez:
3
7
2020
Statut:
ppublish
Résumé
The most common peripheral nervous system manifestations in Sjogren's syndrome are small fiber sensory neuropathies (SFPN) and axonal sensorimotor polyneuropathies. Currently, treatment in small fiber neuropathy is mainly symptomatic and based on anti-depressors and anti-epileptics. The benefit of treatment with polyvalent immunoglobulins for SFPN has been reported in small series of patients, although transient in several cases. The medium-to-long-term effects of polyvalent immunoglobulins (Ig) in SFPN in patients with Sjogren's syndrome who are refractory to conventional treatments remain an unmet medical need. We present our experience related to the persistent improvement of Ig in a case series of SFPN in Sjogren's syndrome and relevant data in the literature regarding the benefits of immunoglobulins, for this indication.
Identifiants
pubmed: 32613444
doi: 10.1007/s00415-020-10033-z
pii: 10.1007/s00415-020-10033-z
doi:
Substances chimiques
Immunoglobulins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM