The optimal vitamin D cut-off value associated with hyperglycemia in an Iranian population.
25(OH)D
25-hydroxyvitamin D
Blood glucose
Cut-off point
Hyperglycemia
Vitamin D
Workers
Journal
Journal of diabetes and metabolic disorders
ISSN: 2251-6581
Titre abrégé: J Diabetes Metab Disord
Pays: Switzerland
ID NLM: 101590741
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
03
06
2019
accepted:
14
08
2019
entrez:
19
6
2020
pubmed:
19
6
2020
medline:
19
6
2020
Statut:
epublish
Résumé
Vitamin D deficiency may accelerate the risk of type 2 diabetes mellitus. The association of vitamin D with hyperglycemia may be influenced by lifestyle. To evaluate the relationship between vitamin D status and hyperglycemia among the workers' population. This was a medical records review of 7054 Iranian factory workers participating in an annual health check-up for employees. Of those, potential participants were included in this analysis if data for serum 25-hydroxyvitamin D [25(OH) D] levels were also available. Data of 429 male participants were used for this analysis. Of those, 61.07% had serum 25(OH)D concentrations lower than the sufficient level [≥20 ng/ml]. Hyperglycemic participants had significantly lower 25(OH)D than those with normal fasting blood glucose (FBG). Regression analyses highlighted serum 25(OH)D as a significant determinant of hyperglycemia [OR: 0.943(0.901, 988); Our results revealed a considerable proportion of participants with serum 25(OH)D below the optimal level as well as a significant inverse association between vitamin D status and hyperglycemia among the factory workers. These findings highlight the importance of including the evaluation of vitamin D status as a part of annual health examinations for employees, and may help health policy- makers prevent or delay type 2 diabetes mellitus among the workers' population.
Sections du résumé
BACKGROUND
BACKGROUND
Vitamin D deficiency may accelerate the risk of type 2 diabetes mellitus. The association of vitamin D with hyperglycemia may be influenced by lifestyle.
OBJECTIVE
OBJECTIVE
To evaluate the relationship between vitamin D status and hyperglycemia among the workers' population.
METHODS
METHODS
This was a medical records review of 7054 Iranian factory workers participating in an annual health check-up for employees. Of those, potential participants were included in this analysis if data for serum 25-hydroxyvitamin D [25(OH) D] levels were also available.
RESULTS
RESULTS
Data of 429 male participants were used for this analysis. Of those, 61.07% had serum 25(OH)D concentrations lower than the sufficient level [≥20 ng/ml]. Hyperglycemic participants had significantly lower 25(OH)D than those with normal fasting blood glucose (FBG). Regression analyses highlighted serum 25(OH)D as a significant determinant of hyperglycemia [OR: 0.943(0.901, 988);
CONCLUSION
CONCLUSIONS
Our results revealed a considerable proportion of participants with serum 25(OH)D below the optimal level as well as a significant inverse association between vitamin D status and hyperglycemia among the factory workers. These findings highlight the importance of including the evaluation of vitamin D status as a part of annual health examinations for employees, and may help health policy- makers prevent or delay type 2 diabetes mellitus among the workers' population.
Identifiants
pubmed: 32550151
doi: 10.1007/s40200-019-00433-y
pii: 433
pmc: PMC7270412
doi:
Types de publication
Journal Article
Langues
eng
Pagination
5-12Informations de copyright
© Springer Nature Switzerland AG 2019.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare to have no competing interests.
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