Tracking of Infused Mesenchymal Stem Cells in Injured Pulmonary Tissue in
Ataxia telangiectasia
Atm
bio imaging
bioluminescence
mesenchymal stromal/stem cells
qRT-PCR
tracking
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
10 06 2020
10 06 2020
Historique:
received:
07
05
2020
revised:
05
06
2020
accepted:
08
06
2020
entrez:
14
6
2020
pubmed:
14
6
2020
medline:
19
3
2021
Statut:
epublish
Résumé
Pulmonary failure is the main cause of morbidity and mortality in the human chromosomal instability syndrome Ataxia-telangiectasia (A-T). Major phenotypes include recurrent respiratory tract infections and bronchiectasis, aspiration, respiratory muscle abnormalities, interstitial lung disease, and pulmonary fibrosis. At present, no effective pulmonary therapy for A-T exists. Cell therapy using adipose-derived mesenchymal stromal/stem cells (ASCs) might be a promising approach for tissue regeneration. The aim of the present project was to investigate whether ASCs migrate into the injured lung parenchyma of
Identifiants
pubmed: 32531978
pii: cells9061444
doi: 10.3390/cells9061444
pmc: PMC7349119
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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