Preterm children's developmental coordination disorder, cognition and quality of life: a prospective cohort study.

neonatology neurodevelopment outcomes research

Journal

BMJ paediatrics open
ISSN: 2399-9772
Titre abrégé: BMJ Paediatr Open
Pays: England
ID NLM: 101715309

Informations de publication

Date de publication:
2020
Historique:
received: 08 01 2020
revised: 28 02 2020
accepted: 02 03 2020
entrez: 11 6 2020
pubmed: 11 6 2020
medline: 11 6 2020
Statut: epublish

Résumé

To evaluate the rate of developmental coordination disorder (DCD) and its correlation to cognition and self-experienced health-related quality of life (HRQoL) in children born very preterm. Prospective follow-up study. Regional population of children born very preterm in Turku University Hospital, Finland, in 2001-2006. A total of 170 children born very preterm were followed up until 11 years of age. Motor and cognitive outcomes were evaluated using the Movement Assessment Battery for Children - Second Edition (Movement ABC-2) and the Wechsler Intelligence Scale for Children - Fourth Edition, respectively, and HRQoL using the 17-Dimensional Illustrated Questionnaire (17D). The Touwen neurological examination was performed to exclude other neurological conditions affecting the motor outcome. Eighteen children born very preterm (17 boys) (11.3%) had DCD, defined as Movement ABC-2 total test score ≤5th percentile. A positive correlation between motor and cognitive outcome (r=0.22, p=0.006) was found. Children born very preterm with DCD had lower cognitive scores than those without DCD (Full-Scale IQ mean 76.8 vs 91.6, p=0.001). Moreover, children born very preterm with DCD reported lower HRQoL than children born very preterm without motor impairment (17D mean 0.93 vs 0.96, p=0.03). However, HRQoL was higher in this group of children born very preterm compared with population-based normative test results (p<0.001). DCD was still common at 11 years of age in children born very preterm in 2000s. DCD associated with adverse cognitive development and lower self-experienced HRQoL. However, this group of children born very preterm reported better HRQoL in comparison with Finnish norms.

Identifiants

pubmed: 32518843
doi: 10.1136/bmjpo-2019-000633
pii: bmjpo-2019-000633
pmc: PMC7254160
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e000633

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Karoliina Uusitalo (K)

Pediatric Neurology, University of Turku, Turku, Finland.
Pediatric Neurology, Turku University Hospital, Turku, Finland.

Leena Haataja (L)

Pediatric Neurology, University of Helsinki, Helsinki, Finland.
Children's Hospital, Pediatric Research Center, Helsinki University Hospital, Helsinki, Uusimaa, Finland.

Anna Nyman (A)

Psychology, University of Turku, Turku, Finland.

Liisi Ripatti (L)

Pediatric Surgery, Turku University Hospital, Turku, Finland.

Mira Huhtala (M)

Oncology and Radiotherapy, Turku University Hospital, Turku, Finland.

Päivi Rautava (P)

Public Health, University of Turku, Turku, Finland.
Clinical Research Center, Turku, Finland.

Liisa Lehtonen (L)

Pediatrics, University of Turku, Turku, Finland.
Pediatrics, Turku University Hospital, Turku, Finland.

Riitta Parkkola (R)

Radiology, University of Turku, Turku, Finland.
Turku PET Centre, Turku, Finland.

Katri Lahti (K)

Pediatric Neurology, University of Turku, Turku, Finland.
Pediatric Neurology, Turku University Hospital, Turku, Finland.

Mari Koivisto (M)

Clinical Science, University of Turku, Turku, Finland.

Sirkku Setänen (S)

Pediatric Neurology, University of Turku, Turku, Finland.
Women's and Children's Health, Uppsala Universitet, Uppsala, Sweden.

Classifications MeSH