Structural basis of HapE


Journal

Life science alliance
ISSN: 2575-1077
Titre abrégé: Life Sci Alliance
Pays: United States
ID NLM: 101728869

Informations de publication

Date de publication:
07 2020
Historique:
received: 02 04 2020
revised: 08 05 2020
accepted: 12 05 2020
entrez: 30 5 2020
pubmed: 30 5 2020
medline: 8 7 2021
Statut: epublish

Résumé

Azoles are first-line therapeutics for human and plant fungal infections, but their broad use has promoted the development of resistances. Recently, a pan-azole-resistant clinical

Identifiants

pubmed: 32467317
pii: 3/7/e202000729
doi: 10.26508/lsa.202000729
pmc: PMC7266990
pii:
doi:

Substances chimiques

Antifungal Agents 0
Azoles 0
CCAAT-Binding Factor 0
Fungal Proteins 0

Banques de données

PDB
['6Y35', '6Y36', '6Y37', '6Y39', '4G92', '4G91']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
ID : 208396/Z/17/Z
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R01 AI143198
Pays : United States

Informations de copyright

© 2020 Hortschansky et al.

Références

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Auteurs

Peter Hortschansky (P)

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), and Friedrich Schiller University Jena, Jena, Germany.

Matthias Misslinger (M)

Institute of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria.

Jasmin Mörl (J)

Institute of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria.

Fabio Gsaller (F)

Institute of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria.

Michael J Bromley (MJ)

Manchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

Axel A Brakhage (AA)

Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), and Friedrich Schiller University Jena, Jena, Germany.

Michael Groll (M)

Center for Integrated Protein Science Munich at the Department Chemistry, Technical University of Munich, Garching, Germany.

Hubertus Haas (H)

Institute of Molecular Biology/Biocenter, Innsbruck Medical University, Innsbruck, Austria.

Eva M Huber (EM)

Center for Integrated Protein Science Munich at the Department Chemistry, Technical University of Munich, Garching, Germany eva.huber@tum.de.

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Classifications MeSH