Dynamic mechanism of halide salts on the phase transition of protein models, poly(N-isopropylacrylamide) and poly(N,N-diethylacrylamide).


Journal

Physical chemistry chemical physics : PCCP
ISSN: 1463-9084
Titre abrégé: Phys Chem Chem Phys
Pays: England
ID NLM: 100888160

Informations de publication

Date de publication:
14 Jun 2020
Historique:
pubmed: 28 5 2020
medline: 24 11 2020
entrez: 28 5 2020
Statut: ppublish

Résumé

The effects of salts on protein systems are not yet fully understood. We investigated the ionic dynamics of three halide salts (NaI, NaBr, and NaCl) with two protein models, namely poly(N-isopropylacrylamide) (PNIPAM) and poly(N,N-diethylacrylamide) (PDEA), using multinuclear NMR, dispersion corrected density functional theory (DFT-D) calculations and dynamic light scattering (DLS) methods. The variation in ionic line-widths and chemical shifts induced by the polymers clearly illustrates that anions rather than cations interact directly with the polymers. From the variable temperature measurements of the NMR transverse relaxation rates of anions, which characterize the polymer-anion interaction intensities, the evolution behaviors of Cl

Identifiants

pubmed: 32458929
doi: 10.1039/d0cp01366h
doi:

Substances chimiques

Acrylamides 0
Acrylic Resins 0
Bromides 0
Polymers 0
Proteins 0
Sodium Compounds 0
poly(N,N-diethylacrylamide) 0
poly-N-isopropylacrylamide 25189-55-3
Sodium Chloride 451W47IQ8X
Sodium Iodide F5WR8N145C
sodium bromide LC1V549NOM

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12644-12650

Auteurs

Xiaoshuang Yan (X)

State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, P. R. China. gyru@wipm.ac.cn jwfeng@wipm.ac.cn.

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Classifications MeSH