Association of Cow's Milk Protein Allergy Prevalence With Socioeconomic Status in a Cohort of Chilean Infants.
Journal
Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
20
5
2020
medline:
22
6
2021
entrez:
20
5
2020
Statut:
ppublish
Résumé
The aim of the study was to compare the cow's milk protein allergy (CMPA) prevalence in 2 cohorts of children from different socioeconomic strata. Prospective birth cohort that included patients from 2 hospitals providing care for a low- and high-income population, respectively. Healthy newborns ≥34 gestational weeks were recruited and followed up to 12 months by a monthly telephone survey. If ≥2 predefined symptoms/signs suggestive of CMPA were detected, the patient was evaluated by a pediatric gastroenterologist. Diagnosis was confirmed by exclusion diet followed by open oral food challenge. Overall the prevalence of CMPA was 5.2%, with a 6 times higher prevalence in the high income cohort (9.2%) compared with the low-income group (1.5%; relative risk 6.2; 95% confidence interval 1.8-20.7; P = 0.0005). All the cases were non-immunoglobulin E-mediated with predominantly gastrointestinal symptoms. High-income cohort did have higher frequency of C-section, mother's previous chronic disease, mother's history of atopy/food allergy, older age, and higher educational level of parents. Parent smoking and presence of pets at home were more frequent in the low-income cohort. Multiple logistic regression showed that the high-income cohort did have older age and higher educational level of both parents. In these cohorts the prevalence of CMPA was higher than reported previously in other developing countries and significantly higher in the high-income group. Our findings were associated with sociodemographic characteristics of the parents.
Identifiants
pubmed: 32427653
doi: 10.1097/MPG.0000000000002787
pii: 00005176-202009000-00023
doi:
Substances chimiques
Milk Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e80-e83Références
Nwaru BI, Hickstein L, Panesar SS, et al. Prevalence of common food allergies in Europe: a systematic review and meta-analysis. Allergy 2014; 69:992–1007.
Schoemaker AA, Sprikkelman AB, Grimshaw KE, et al. Incidence and natural history of challenge-proven cow's milk allergy in European children—EuroPrevall birth cohort. Allergy 2015; 70:963–972.
Acevedo N, Sánchez J, Zakzuk J, et al. Particular characteristics of allergic symptoms in tropical environments: follow up to 24 months in the FRAAT birth cohort study. BMC Pulm Med 2012; 12:13.
Mehaudy R, Parisi C, Petriz N, et al. Prevalence of cow's milk protein allergy among children in a university community hospital. Arch Argent Pediatr 2018; 116:219–223.
Gonçalves LCP, Guimarães TCP, Silva RM, et al. Prevalence of food allergy in infants and pre-schoolers in Brazil. Allergol Immunopathol (Madr) 2016; 44:497–503.
Iweala OI, Burks AW. Food allergy: our evolving understanding of its pathogenesis, prevention, and treatment. Curr Allergy Asthma Rep 2016; 16:37.
Ministry of Social Development and Family. CASEN Survey 2017 [Internet] [cited October 28, 2019]. http://observatorio.ministeriodesarrollosocial.gob.cl/casen-multidimensional/casen.
Venkataraman D, Erlewyn-Lajeunesse M, Kurukulaaratchy RJ, et al. Prevalence and longitudinal trends of food allergy during childhood and adolescence: Results of the Isle of Wight Birth Cohort Study. Clin Exp Allergy 2018; 48:394–402.
Koletzko S, Heine RG. Non-IgE mediated cow's milk allergy in EuroPrevall. Allergy 2015; 70:1679–1680.
Chen J, Hu Y, Allen KJ, et al. The prevalence of food allergy in infants in Chongqing, China: the prevalence of food allergy. Pediatr Allergy Immunol 2011; 22:356–360.
NIAID-Sponsored Expert Panel, Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol 2010; 126: (6 suppl): S1–S58.
Ardura-Garcia C, Garner P, Cooper PJ. Is childhood wheeze and asthma in Latin America associated with poor hygiene and infection? A systematic review. BMJ Open Respir Res 2018; 5:e000249.
Leung TF, Yung E, Wong YS, et al. Parent-reported adverse food reactions in Hong Kong Chinese pre-schoolers: epidemiology, clinical spectrum and risk factors. Pediatr Allergy Immunol 2009; 20:339–346.
Sardecka I, Łoś-Rycharska E, Ludwig H, et al. Early risk factors for cow's milk allergy in children in the first year of life. Allergy Asthma Proc 2018; 39:e44–e54.
Ben-Shoshan M, Harrington DW, Soller L, et al. Demographic predictors of peanut, tree nut, fish, shellfish, and sesame allergy in Canada. J Allergy 2012; 2012:858306.
Pawlinska-Chmara R, Wronka I, Muc M. Prevalence and correlates of allergic diseases among children. J Physiol Pharmacol Off J Pol Physiol Soc 2008; 59: (suppl 6): 549–556.
Dom S, Droste JHJ, Sariachvili MA, et al. The influence of parental educational level on the development of atopic sensitization, wheezing and eczema during the first year of life. Pediatr Allergy Immunol 2009; 20:438–447.
Shao Y, Forster SC, Tsaliki E, et al. Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth. Nature 2019; 574:117–121.
Musso P, Chiappini E, Bernardini R. Human microbiome and allergic diseases in children: pathogenetic role and therapeutic options. Current Pediatric Reviews 2019; 15:1315666191025110849.
Peters RL, Koplin JJ, Gurrin LC, et al. The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up. J Allergy Clin Immunol 2017; 140:145.e8–153.e8.