Clinical validity of systemic arterial steal among extremely preterm infants with persistent patent ductus arteriosus.
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
10
01
2020
accepted:
11
03
2020
revised:
06
03
2020
pubmed:
13
5
2020
medline:
1
9
2021
entrez:
13
5
2020
Statut:
ppublish
Résumé
Investigate relevance of diastolic flow abnormalities in celiac trunk (aCT) and middle cerebral artery (aMCA) among preterms with persistent hemodynamically significant patent ductus arteriosus (phsPDA, diameter ≥ 1.5 mm, and age ≥ 7 days). Five hundred fifteen echocardiograms from 156 neonates born <28 weeks gestation age (GA) were analyzed retrospectively. Infants with aCT or aMCA at any time were compared with the rest. Separate comparisons were performed for aCT and aMCA. Primary outcome was composite of death, chronic lung disease (CLD), or necrotizing enterocolitis ≥ stage 2. Logistic regression was used to adjust for confounders. Mean (SD) weight and GA were 820(214) g and 25.2(1.3) weeks. aMCA, but not aCT, was associated with primary outcome [adjusted odds ratio 2.17, 95% CI: 1.01-4.67] and CLD [2.20 (0.99-4.87)]. aMCA may be a valid marker for defining the clinical significance of phsPDA in preterm neonates. aCeT may be of limited value in selecting patients for treatment.
Identifiants
pubmed: 32393829
doi: 10.1038/s41372-020-0663-8
pii: 10.1038/s41372-020-0663-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
84-92Références
Zonnenberg I, de Waal K. The definition of a haemodynamic significant duct in randomized controlled trials: a systematic literature review. Acta Paediatr. 2012;101:247–51.
doi: 10.1111/j.1651-2227.2011.02468.x
Sehgal A, McNamara PJ. Does echocardiography facilitate determination of hemodynamic significance attributable to the ductus arteriosus? Eur J Pediatr. 2009;168:907–14.
doi: 10.1007/s00431-009-0983-3
Kluckow M, Evans N. Early echocardiographic prediction of symptomatic patent ductus arteriosus in preterm infants undergoing mechanical ventilation. J Pediatr. 1995;127:774–9.
doi: 10.1016/S0022-3476(95)70172-9
El-Khuffash A, James AT, Corcoran JD, Dicker P, Franklin O, Elsayed YN, et al. A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 2015;167:1354–61.e2.
doi: 10.1016/j.jpeds.2015.09.028
Sehgal A, Paul E, Menahem S. Functional echocardiography in staging for ductal disease severity: role in predicting outcomes. Eur J Pediatr. 2013;172:179–84.
doi: 10.1007/s00431-012-1851-0
Carlo WF, Kimball TR, Michelfelder EC, Border WL. Persistent diastolic flow reversal in abdominal aortic Doppler-flow profiles is associated with an increased risk of necrotizing enterocolitis in term infants with congenital heart disease. Pediatrics 2007;119:330–5.
doi: 10.1542/peds.2006-2640
Coombs RC, Morgan ME, Durbin GM, Booth IW, McNeish AS. Gut blood flow velocities in the newborn: effects of patent ductus arteriosus and parenteral indomethacin. Arch Dis Child. 1990;65:1067–71.
doi: 10.1136/adc.65.10_Spec_No.1067
Shimada S, Kasai T, Konishi M, Fujiwara T. Effects of patent ductus arteriosus on left ventricular output and organ blood flows in preterm infants with respiratory distress syndrome treated with surfactant. J Pediatr. 1994;125:270–7.
doi: 10.1016/S0022-3476(94)70210-1
El-Khuffash A, Higgins M, Walsh K, Molloy EJ. Quantitative assessment of the degree of ductal steal using celiac artery blood flow to left ventricular output ratio in preterm infants. Neonatology. 2008;93:206–12.
doi: 10.1159/000110869
Perlman JM, Hill A, Volpe JJ. The effect of patent ductus arteriosus on flow velocity in the anterior cerebral arteries: ductal steal in the premature newborn infant. J Pediatr. 1981;99:767–71.
doi: 10.1016/S0022-3476(81)80408-8
Weir FJ, Ohlsson A, Myhr TL, Fong K, Ryan ML. A patent ductus arteriosus is associated with reduced middle cerebral artery blood flow velocity. Eur J Pediatr. 1999;158:484–7.
doi: 10.1007/s004310051125
Hsu KH, Nguyen J, Dekom S, Ramanathan R, Noori S. Effects of patent ductus arteriosus on organ blood flow in infants born very preterm: a prospective study with serial echocardiography. J Pediatr. 2020;216:95–100.e2.
doi: 10.1016/j.jpeds.2019.08.057
Lee SK, McMillan DD, Ohlsson A, Pendray M, Synnes A, Whyte R, et al. Variations in practice and outcomes in the Canadian NICU network: 1996–1997. Pediatrics 2000;106:1070–9.
doi: 10.1542/peds.106.5.1070
Shah PS, Seidlitz W, Chan P, Yeh S, Musrap N, Lee SK, et al. Internal audit of the canadian neonatal network data collection system. Am J Perinatol. 2017;34:1241–9.
doi: 10.1055/s-0037-1603325
Lipman B, Serwer GA, Brazy JE. Abnormal cerebral hemodynamics in preterm infants with patent ductus arteriosus. Pediatrics. 1982;69:778–81.
pubmed: 7079043
Shortland DB, Gibson NA, Levene MI, Archer LN, Evans DH, Shaw DE. Patent ductus arteriosus and cerebral circulation in preterm infants. Dev Med Child Neurol. 1990;32:386–93.
doi: 10.1111/j.1469-8749.1990.tb16957.x
Martin CG, Snider AR, Katz SM, Peabody JL, Brady JP. Abnormal cerebral blood flow patterns in preterm infants with a large patent ductus arteriosus. J Pediatr. 1982;101:587–93.
doi: 10.1016/S0022-3476(82)80715-4
Wong SN, Lo RN, Hui PW. Abnormal renal and splanchnic arterial Doppler pattern in premature babies with symptomatic patent ductus arteriosus. J Ultrasound Med. 1990;9:125–30.
doi: 10.7863/jum.1990.9.3.125
Hoodbhoy SA, Cutting HA, Seddon JA, Campbell ME. Cerebral and splanchnic hemodynamics after duct ligation in very low birth weight infants. J Pediatr. 2009;154:196–200.
doi: 10.1016/j.jpeds.2008.07.051
Jim WT, Chiu NC, Chen MR, Hung HY, Kao HA, Hsu CH, et al. Cerebral hemodynamic change and intraventricular hemorrhage in very low birth weight infants with patent ductus arteriosus. Ultrasound Med Biol. 2005;31:197–202.
doi: 10.1016/j.ultrasmedbio.2004.10.006
Schena F, Francescato G, Cappelleri A, Picciolli I, Mayer A, Mosca F, et al. Association between hemodynamically significant patent ductus arteriosus and Bronchopulmonary Dysplasia. J Pediatr. 2015;166:1488–92.
doi: 10.1016/j.jpeds.2015.03.012
Broadhouse KM, Price AN, Durighel G, Cox DJ, Finnemore AE, Edwards AD, et al. Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 2013;26:1135–41.
doi: 10.1002/nbm.2927
Louis D, Mukhopadhyay K, Sodhi KS, Jain V, Kumar P. Superior mesenteric artery Doppler is poor at predicting feed intolerance and NEC in preterm small for gestational age neonates. J Matern Fetal Neonatal Med. 2013;26:1855–9.
doi: 10.3109/14767058.2013.799649
Clyman R, Wickremasinghe A, Jhaveri N, Hassinger DC, Attridge JT, Sanocka U, et al. Enteral feeding during indomethacin and ibuprofen treatment of a patent ductus arteriosus. J Pediatr. 2013;163:406–11.
doi: 10.1016/j.jpeds.2013.01.057
Sellmer A, Bjerre JV, Schmidt MR, McNamara PJ, Hjortdal VE, Host B, et al. Morbidity and mortality in preterm neonates with patent ductus arteriosus on day 3. Arch Dis Child Fetal Neonatal Ed. 2013;98:F505–10.
doi: 10.1136/archdischild-2013-303816
Benitz WE. Learning to live with patency of the ductus arteriosus in preterm infants. J Perinatol. 2011;31:S42–8.
doi: 10.1038/jp.2010.175