Factors Associated With Time to Pregnancy in Women With Axial Spondyloarthritis: A Registry-Based Multicenter Study.
Adult
Age Factors
Antirheumatic Agents
/ adverse effects
Arthritis, Rheumatoid
/ diagnosis
Female
Humans
Infertility, Female
/ diagnosis
Norway
/ epidemiology
Parity
Pregnancy
Prospective Studies
Registries
Retrospective Studies
Risk Assessment
Risk Factors
Spondylarthritis
/ diagnosis
Time Factors
Time-to-Pregnancy
Young Adult
Journal
Arthritis care & research
ISSN: 2151-4658
Titre abrégé: Arthritis Care Res (Hoboken)
Pays: United States
ID NLM: 101518086
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
15
07
2019
accepted:
21
04
2020
pubmed:
1
5
2020
medline:
14
9
2021
entrez:
1
5
2020
Statut:
ppublish
Résumé
The present study was undertaken to study time to pregnancy (TTP) and factors associated with TTP in women with axial spondyloarthritis (SpA) compared to women with rheumatoid arthritis (RA). We included 274 women with axial SpA and 317 women with RA from the Norwegian nationwide registry RevNatus. For all the women, we had retrospectively collected data on TTP, and a subgroup also had prospectively collected data. We compared TTP in women with axial SpA to women with RA using Kaplan-Meier plots and a log rank test. To identify factors associated with TTP, we used Cox proportional hazards regression. TTP exceeded 12 months in 21% of women with axial SpA. In the subgroup followed prospectively, 32% had TTP that exceeded 12 months. Longer TTP was associated with older age, nulliparity, and longer disease duration, with hazard ratios of 0.97 (95% confidence interval [95% CI] 0.94-1.00), 0.66 (95% CI 0.50-0.88), and 0.94 (95% CI 0.91-0.98), respectively. Disease activity, medication, and self-reported health-related quality of life were not associated with TTP. We found no statistically significant differences between axial SpA and RA in regard to TTP. In women with axial SpA, longer TTP was associated with older age, nulliparity, and longer disease duration.
Substances chimiques
Antirheumatic Agents
0
Types de publication
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1201-1209Informations de copyright
© 2020 The Authors. Arthritis Care & Research published by Wiley Periodicals LLC on behalf of American College of Rheumatology.
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