Performance of a Biodegradable Composite with Hydroxyapatite as a Scaffold in Pulp Tissue Repair.

RNA sequence polymer complex pulp capping tertiary dentin

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
17 Apr 2020
Historique:
received: 30 03 2020
revised: 14 04 2020
accepted: 15 04 2020
entrez: 23 4 2020
pubmed: 23 4 2020
medline: 23 4 2020
Statut: epublish

Résumé

Vital pulp therapy is an important endodontic treatment. Strategies using growth factors and biological molecules are effective in developing pulp capping materials based on wound healing by the dentin-pulp complex. Our group developed biodegradable viscoelastic polymer materials for tissue-engineered medical devices. The polymer contents help overcome the poor fracture toughness of hydroxyapatite (HAp)-facilitated osteogenic differentiation of pulp cells. However, the composition of this novel polymer remained unclear. This study evaluated a novel polymer composite, P(CL-

Identifiants

pubmed: 32316615
pii: polym12040937
doi: 10.3390/polym12040937
pmc: PMC7240495
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Japan Society for the Promotion of Science
ID : JP19K18995, 17K11704, 18K14061 and 17K10729.
Organisme : SECOM Science and Technology Foundation
ID : 2019, 2nd year
Organisme : Japan Agency for Medical Research and Development
ID : JP18gm5810017.

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Auteurs

Motoki Okamoto (M)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Sayako Matsumoto (S)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Ayato Sugiyama (A)

Department of Basic Medicinal Science, Nagoya University, Chikusa, Nagoya 464-8601, Japan.

Kei Kanie (K)

Department of Basic Medicinal Science, Nagoya University, Chikusa, Nagoya 464-8601, Japan.

Masakatsu Watanabe (M)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Hailing Huang (H)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Manahil Ali (M)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Yuki Ito (Y)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Jiro Miura (J)

Division for Interdisciplinary Dentistry, Osaka University Dental Hospital, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan.

Yujiro Hirose (Y)

Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.

Koichiro Uto (K)

International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 1 Chome-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.

Mitsuhiro Ebara (M)

International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 1 Chome-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.

Ryuji Kato (R)

Department of Basic Medicinal Science, Nagoya University, Chikusa, Nagoya 464-8601, Japan.
Institute of Nano-Life-Systems, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

Aika Yamawaki-Ogata (A)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

Yuji Narita (Y)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

Shigetada Kawabata (S)

Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.

Yusuke Takahashi (Y)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Mikako Hayashi (M)

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan.

Classifications MeSH