Pesticide use and risk of Hodgkin lymphoma: results from the North American Pooled Project (NAPP).

Adult Canada / epidemiology Environmental Exposure / statistics & numerical data Hodgkin Disease / epidemiology Humans Kansas / epidemiology Nebraska / epidemiology Pesticides
Cancer Case–control Hodgkin lymphoma Insecticide Organophosphate Pesticide

Journal

Cancer causes & control : CCC
ISSN: 1573-7225
Titre abrégé: Cancer Causes Control
Pays: Netherlands
ID NLM: 9100846

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 04 07 2019
accepted: 07 04 2020
pubmed: 22 4 2020
medline: 22 8 2020
entrez: 22 4 2020
Statut: ppublish

Résumé

The purpose of this study was to investigate associations between pesticide exposures and risk of Hodgkin lymphoma (HL) using data from the North American Pooled Project (NAPP). Three population-based studies conducted in Kansas, Nebraska, and six Canadian provinces (HL = 507, Controls = 3886) were pooled to estimate odds ratios and 95% confidence intervals for single (never/ever) and multiple (0, 1, 2-4, ≥ 5) pesticides used, duration (years) and, for select pesticides, frequency (days/year) using adjusted logistic regression models. An age-stratified analysis (≤ 40/ > 40 years) was conducted when numbers were sufficient. In an analysis of 26 individual pesticides, ever use of terbufos was significantly associated with HL (OR: 2.53, 95% CI 1.04-6.17). In age-stratified analyses, associations were stronger among those ≤ 40 years of age. No significant associations were noted among those > 40 years old; however, HL cases ≤ 40 were three times more likely to report ever using dimethoate (OR: 3.76 95% CI 1.02-33.84) and almost twice as likely to have ever used malathion (OR: 1.86 95% CI 1.00-3.47). Those ≤ 40 years of age reporting use of 5 + organophosphate insecticides had triple the odds of HL (OR: 3.00 95% CI 1.28-7.03). Longer duration of use of 2,4-D, ≥ 6 vs. 0 years, was associated with elevated odds of HL (OR: 2.59 95% CI 1.34-4.97). In the NAPP, insecticide use may increase the risk of HL, but results are based on small numbers.

Identifiants

DOI: 10.1007/s10552-020-01301-4 PMID: 32314107 PMC: PMC7183499
pubmed: 32314107
doi: 10.1007/s10552-020-01301-4
pii: 10.1007/s10552-020-01301-4
pmc: PMC7183499
doi:

Substances chimiques

Pesticides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

583-599

Subventions

Organisme : Canadian Cancer Society
ID : 703055

Références

Cancer Epidemiol Biomarkers Prev. 2001 Nov;10(11):1155-63
pubmed: 11700263
J Environ Sci Health B. 2004 Jan;39(1):53-64
pubmed: 15022740
Int J Environ Res Public Health. 2011 Sep;8(9):3579-90
pubmed: 22016704
Scand J Work Environ Health. 1992 Aug;18(4):209-15
pubmed: 1411362
Environ Health Perspect. 2007 Dec;115(12):1787-93
pubmed: 18087601
Occup Environ Med. 2015 Feb;72(2):81-2
pubmed: 25540410
Annu Rev Public Health. 2004;25:155-97
pubmed: 15015917
Environ Health Perspect. 1994 Apr;102(4):380-3
pubmed: 7925178
Lancet Oncol. 2015 May;16(5):490-1
pubmed: 25801782
J Agromedicine. 2012 Jan;17(1):30-9
pubmed: 22191501
J Natl Cancer Inst. 2018 May 1;110(5):509-516
pubmed: 29136183
Int J Mol Med. 2016 Oct;38(4):1012-20
pubmed: 27600395
Biomed Res Int. 2014;2014:179691
pubmed: 24719846
PLoS One. 2014 Oct 22;9(10):e109332
pubmed: 25337994
Chin J Cancer. 2014 Dec;33(12):591-7
pubmed: 25418190
Front Pharmacol. 2014 Jun 23;5:145
pubmed: 25002848
Teratog Carcinog Mutagen. 2000;20(4):229-40
pubmed: 10910473
Int Arch Occup Environ Health. 2002 Aug;75(6):406-14
pubmed: 12070637
BMC Cancer. 2017 May 19;17(1):343
pubmed: 28525996
J Proteomics. 2011 Nov 18;74(12):2713-22
pubmed: 21989265
Mutat Res. 2002 Nov 26;521(1-2):165-78
pubmed: 12438013
Epidemiology. 1999 Jan;10(1):37-48
pubmed: 9888278
BMC Cancer. 2009 May 11;9:141
pubmed: 19432977
Scand J Work Environ Health. 2005;31 Suppl 1:98-104; discussion 63-5
pubmed: 16190155
Eur J Haematol Suppl. 2005 Jul;(66):34-41
pubmed: 16007866
Environ Toxicol. 2013 Oct;28(10):543-52
pubmed: 21786386
J Environ Sci Health B. 2016;51(6):402-34
pubmed: 27015139
Occup Med. 1991 Jul-Sep;6(3):335-54
pubmed: 1835166
Cancer Causes Control. 2000 Apr;11(4):373-80
pubmed: 10843448
Occup Environ Med. 2009 May;66(5):291-8
pubmed: 19017688
PLoS One. 2014 May 02;9(5):e96580
pubmed: 24794244
Cancer Res. 1992 May 1;52(9):2447-55
pubmed: 1568215
Am J Epidemiol. 2009 May 15;169(10):1182-90
pubmed: 19363102
Environ Health Perspect. 2012 Apr;120(4):515-20
pubmed: 22262687
J Occup Environ Med. 1995 Feb;37(2):126-7
pubmed: 7655952
J Occup Environ Med. 2006 Mar;48(3):264-74
pubmed: 16531830
Occup Environ Med. 2011 Jul;68(7):537-41
pubmed: 21257983
Cancer Epidemiol. 2017 Aug;49:175-185
pubmed: 28709062
Int J Cancer. 2007 Oct 15;121(8):1799-805
pubmed: 17534892
Scand J Work Environ Health. 1985 Dec;11(6):397-407
pubmed: 3912986
Environ Health Perspect. 2009 Dec;117(12):1809-13
pubmed: 20049197
Int J Environ Res Public Health. 2011 Jun;8(6):2265-303
pubmed: 21776230
Lancet. 1991 Jul 27;338(8761):223-7
pubmed: 1676786
Occup Environ Med. 2015 Oct;72(10):736-44
pubmed: 26150671
JAMA. 1986 Sep 5;256(9):1141-7
pubmed: 3801091
Environ Health Perspect. 2008 Aug;116(8):1001-8
pubmed: 18709150
Cancer Causes Control. 1997 May;8(3):420-43
pubmed: 9498903
Am J Epidemiol. 2013 Jan 1;177(1):59-74
pubmed: 23171882
Environ Toxicol Pharmacol. 2013 Nov;36(3):796-800
pubmed: 23958972
Toxicol Mech Methods. 2016 Oct;26(8):588-594
pubmed: 27603568
Epidemiology. 1993 Jan;4(1):55-62
pubmed: 8420582
CA Cancer J Clin. 2013 Mar-Apr;63(2):120-42
pubmed: 23322675
J Toxicol Environ Health B Crit Rev. 2012;15(4):238-63
pubmed: 22571220
Epidemiology. 2006 Jan;17(1):69-74
pubmed: 16357597
J Agromedicine. 2009;14(2):125-31
pubmed: 19437268
Environ Health Perspect. 2006 Dec;114(12):1838-42
pubmed: 17185272
Environ Health Perspect. 2001 Oct;109(10):1071-8
pubmed: 11689348
Environ Health Perspect. 2000 Apr;108(4):293-300
pubmed: 10753086
BMC Med Res Methodol. 2008 Oct 30;8:70
pubmed: 18973665
Int J Cancer. 2016 Oct 15;139(8):1703-14
pubmed: 27261772
Am J Epidemiol. 2004 Nov 1;160(9):876-85
pubmed: 15496540
Scand J Work Environ Health. 1985 Apr;11(2):131-3
pubmed: 4001901
J Occup Med Toxicol. 2017 Nov 23;12:31
pubmed: 29201133
Am J Epidemiol. 2009 Aug 15;170(4):501-6
pubmed: 19561065
Environ Res. 2006 Sep;102(1):70-6
pubmed: 16620808
Toxicol Lett. 2014 Oct 15;230(2):157-65
pubmed: 24269242
PLoS One. 2012;7(11):e49405
pubmed: 23185328
Prostate. 2011 Feb 1;71(2):168-83
pubmed: 20799287
Toxicology. 2013 May 10;307:89-94
pubmed: 23041710
Cancer Causes Control. 2010 Jun;21(6):871-7
pubmed: 20155313
J Environ Sci Health B. 2012;47(5):445-54
pubmed: 22424070
Cancer Causes Control. 2013 Sep;24(9):1661-73
pubmed: 23756639
Epidemiology. 1990 Sep;1(5):349-56
pubmed: 2078610
Inflamm Res. 2014 Nov;63(11):895-7
pubmed: 25138977
Int J Cancer. 2012 Dec 1;131(11):2650-9
pubmed: 22396152
Environ Mol Mutagen. 2008 Jun;49(5):360-7
pubmed: 18418871

Auteurs

Lidija Latifovic (L)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada.
Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, M5T 3M7, Canada.

Laura E Beane Freeman (LEB)

Division of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, MD, USA.

John J Spinelli (JJ)

Population Oncology, BC Centre, Vancouver, BC, Canada.
School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.

Manisha Pahwa (M)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada.
Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, ON, Canada.

Linda Kachuri (L)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada.
Department of Epidemiology & Biostatistics, University of California At San Francisco, San Francisco, CA, USA.

Aaron Blair (A)

Division of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, MD, USA.

Kenneth P Cantor (KP)

Division of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, MD, USA.

Shelia Hoar Zahm (SH)

Shelia Zahm Consulting, Hermon, ME, USA.

Dennis D Weisenburger (DD)

Department of Pathology, City of Hope Medical Center, Duarte, CA, USA.

John R McLaughlin (JR)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada.
Public Health Ontario, Toronto, ON, Canada.
Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, M5T 3M7, Canada.

James A Dosman (JA)

University of Saskatchewan, Saskatoon, SK, Canada.

Punam Pahwa (P)

University of Saskatchewan, Saskatoon, SK, Canada.

Stella Koutros (S)

Division of Cancer Epidemiology and Genetics, U.S. National Cancer Institute, Bethesda, MD, USA.

Paul A Demers (PA)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada.
Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, M5T 3M7, Canada.

Shelley A Harris (SA)

Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, ON, Canada. shelley.harris@utoronto.ca.
Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, M5T 3M7, Canada. shelley.harris@utoronto.ca.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

Recherchemedicale.com › Personnes › Tranches d'âge › Adulte › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Régions géographiques › Amériques › Amérique du Nord › Canada › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Environnement et santé publique › Santé publique › Pollution de l'environnement › Exposition environnementale › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Lymphomes › Maladie de Hodgkin › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Régions géographiques › Amériques › Amérique du Nord › États-Unis › États du Centre-Ouest des États-Unis › Kansas › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Régions géographiques › Amériques › Amérique du Nord › États-Unis › États du Centre-Ouest des États-Unis › Nébraska › Pesticide use and risk of Hodgkin lymphoma:...
Recherchemedicale.com › Actions chimiques et utilisations › Actions toxiques › Pesticides › Pesticide use and risk of Hodgkin lymphoma:...