Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati.
Adolescent
Adult
Aged
Aged, 80 and over
Betacoronavirus
COVID-19
Child
Child, Preschool
Coronavirus Infections
/ epidemiology
Female
Hematology
/ organization & administration
Hospitals
Humans
Infant
Infant, Newborn
Infection Control
/ methods
Italy
/ epidemiology
Male
Medical Oncology
/ organization & administration
Middle Aged
Neoplasms
/ complications
Outpatients
Pandemics
/ prevention & control
Pediatrics
/ organization & administration
Pneumonia, Viral
/ epidemiology
SARS-CoV-2
Stem Cell Transplantation
Transplantation
Young Adult
Journal
Bone marrow transplantation
ISSN: 1476-5365
Titre abrégé: Bone Marrow Transplant
Pays: England
ID NLM: 8702459
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
24
03
2020
accepted:
30
03
2020
revised:
26
03
2020
pubmed:
22
4
2020
medline:
21
10
2020
entrez:
22
4
2020
Statut:
ppublish
Résumé
Italy is the second exposed country worldwide, after China, and Lombardia is the most affected region in Italy, with more than half of the national cases, with 13% of whom being healthcare professionals. The Clinica Pediatrica Università degli Studi di Milano Bicocca is a general pediatric and hematology oncology and transplant center embedded within the designated COVID-19 general Hospital San Gerardo in Monza, located in Lombardia, Italy. Preventive and control measures specifically undertaken to cope with the emergency within hemato-oncology, transplant, and outpatient unit in the pediatric department have been described. Preliminary COVID-19 experiences with the first Italian pediatric hemato-oncology patients are reported. The few available data regarding pediatrics and specifically hemato-oncological patients are discussed. The purpose of this report is to share pediatric hemato-oncology issues encountered in the first few weeks of the COVID-19 outbreak in Italy and to alert healthcare professionals worldwide to be prepared accordingly.
Identifiants
pubmed: 32313181
doi: 10.1038/s41409-020-0895-4
pii: 10.1038/s41409-020-0895-4
pmc: PMC7167532
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1900-1905Commentaires et corrections
Type : CommentIn
Références
WHO Dashboard COVID-19. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 .
ISS—COVID-19 Italian epidemiological report. https://www.epicentro.iss.it/coronavirus/sars-cov-2-sorveglianza-dati .
Grasselli G, Pesenti A, Cecconi M. Critical Care Utilization for the COVID-19 outbreak in Lombardy, Italy: early experience and forecast during an emergency response. JAMA. 2020. https://doi.org/10.1001/jama.2020.4031 [Epub ahead of print].
Coronavirus disease COVID-19: EBMT recommendations. https://www.ebmt.org/ebmt/news/coronavirus-disease-covid-19-ebmt-recommendations-update-march-16-2020 .
Italian Transplant Authority guidelines COVID-19. http://www.trapianti.salute.gov.it/imgs/C_17_cntAvvisi_231_0_file.pdf .
Interim guidelines for COVID-19 management in hematopoietic cell transplant and cellular therapy patients. https://www.astct.org/connect/astct-response-to-covid-19 .
Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ, HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020. https://doi.org/10.1016/S0140-6736(20)30628-0 .
Liu W, Zhang Q, Chen J, Xiang R, Song H, Shu S, et al. Detection of Covid-19 in children in early January 2020 in Wuhan, China. N Engl J Med. 2020. https://doi.org/10.1056/NEJMc2003717 .
Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, Chinese Pediatric Novel Coronavirus Study Team, et al. SARS-CoV-2 infection in children. N Engl J Med. 2020. https://doi.org/10.1056/NEJMc2005073 .
Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020. https://doi.org/10.1001/jama.2020.2648 .
Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics. 2020. https://doi.org/10.1542/peds.2020-0702 .
Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol. 2020;21:335–7. https://doi.org/10.1016/S1470-2045(20)30096-6 .
doi: 10.1016/S1470-2045(20)30096-6
pubmed: 7159000
pmcid: 7159000
Yang C, Li C, Wang S, National Clinical Research Center for Child Health and Disorders and Children’s Oncology Committee of Chinese Research Hospital Association. Clinical strategies for treating pediatric cancer during the outbreak of 2019 novel coronavirus infection. Pediatr Blood Cancer. 2020:e28248. https://doi.org/10.1002/pbc.28248 .
D’Antiga L. Coronaviruses and immunosuppressed patients. The facts during the third epidemic. Liver Transpl. 2020. https://doi.org/10.1002/lt.25756 .
Remuzzi A, Remuzzi G. COVID-19 and Italy: what next? Lancet. 2020. https://doi.org/10.1016/S0140-6736(20)30627-9 .
The Lancet. COVID-19: fighting panic with information. Lancet. 2020;395:537. https://doi.org/10.1016/S0140-6736(20)30379-2 .
doi: 10.1016/S0140-6736(20)30379-2
pubmed: 32087777
pmcid: 7138040
The Lancet Infectious D. COVID-19, a pandemic or not? Lancet Infect Dis. 2020. https://doi.org/10.1016/S1473-3099(20)30180-8 .
Jones DS. History in a crisis—lessons for Covid-19. N Engl J Med. 2020. https://doi.org/10.1056/NEJMp2004361 .