Anti-DENV and Anti-Dengue Vector Activity of Some Heterocyclic Scaffolds.
Arbovirus
DENV
NTDs
anti-viral
dengue infection
heterocyclic
Journal
Mini reviews in medicinal chemistry
ISSN: 1875-5607
Titre abrégé: Mini Rev Med Chem
Pays: Netherlands
ID NLM: 101094212
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
09
2019
revised:
13
12
2019
accepted:
15
01
2020
pubmed:
15
4
2020
medline:
4
2
2021
entrez:
15
4
2020
Statut:
ppublish
Résumé
Dengue is a major health threat related to arbovirus and is endemic in more than 100 countries with an annual estimated above 390 million incidences of infection all around the world. During the period 1996-2015, a considerable increase in the number of dengue cases (more than 500%) was reported in India. Information about dengue disease burden, its prevalence, incidence and geographic distribution is critical in planning appropriate control measures against dengue fever. Till date, no specific treatment for dengue fever is available in any system of medicine, which can be accepted globally. Therefore, safe, cost-effective, and efficacious agents possessing anti-viral potential against dengue virus are needed to be searched in order to fight the dengue infection globally. The aim of the present review is to systematically revise the published research work available concerning the development and evaluation of some heterocyclic scaffolds in the management of dengue.
Identifiants
pubmed: 32286943
pii: MRMC-EPUB-105814
doi: 10.2174/1389557520666200414162408
doi:
Substances chimiques
Antiviral Agents
0
Heterocyclic Compounds
0
Nucleotides
0
Purines
0
purine
W60KTZ3IZY
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1062-1071Informations de copyright
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