The application of digital health to the assessment and treatment of substance use disorders: The past, current, and future role of the National Drug Abuse Treatment Clinical Trials Network.
Journal
Journal of substance abuse treatment
ISSN: 1873-6483
Titre abrégé: J Subst Abuse Treat
Pays: United States
ID NLM: 8500909
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
31
10
2019
revised:
30
01
2020
accepted:
08
02
2020
entrez:
30
3
2020
pubmed:
30
3
2020
medline:
29
7
2021
Statut:
ppublish
Résumé
The application of digital technologies to better assess, understand, and treat substance use disorders (SUDs) is a particularly promising and vibrant area of scientific research. The National Drug Abuse Treatment Clinical Trials Network (CTN), launched in 1999 by the U.S. National Institute on Drug Abuse, has supported a growing line of research that leverages digital technologies to glean new insights into SUDs and provide science-based therapeutic tools to a diverse array of persons with SUDs. This manuscript provides an overview of the breadth and impact of research conducted in the realm of digital health within the CTN. This work has included the CTN's efforts to systematically embed digital screeners for SUDs into general medical settings to impact care models across the nation. This work has also included a pivotal multi-site clinical trial conducted on the CTN platform, whose data led to the very first "prescription digital therapeutic" authorized by the U.S. Food and Drug Administration (FDA) for the treatment of SUDs. Further CTN research includes the study of telehealth to increase capacity for science-based SUD treatment in rural and under-resourced communities. In addition, the CTN has supported an assessment of the feasibility of detecting cocaine-taking behavior via smartwatch sensing. And, the CTN has supported the conduct of clinical trials entirely online (including the recruitment of national and hard-to-reach/under-served participant samples online, with remote intervention delivery and data collection). Further, the CTN is supporting innovative work focused on the use of digital health technologies and data analytics to identify digital biomarkers and understand the clinical trajectories of individuals receiving medications for opioid use disorder (OUD). This manuscript concludes by outlining the many potential future opportunities to leverage the unique national CTN research network to scale-up the science on digital health to examine optimal strategies to increase the reach of science-based SUD service delivery models both within and outside of healthcare.
Identifiants
pubmed: 32220409
pii: S0740-5472(19)30582-3
doi: 10.1016/j.jsat.2020.02.005
pmc: PMC7134325
mid: NIHMS1568666
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
4-11Subventions
Organisme : NIDA NIH HHS
ID : UG1 DA040314
Pays : United States
Organisme : NIDA NIH HHS
ID : UG1 DA040309
Pays : United States
Organisme : NIDA NIH HHS
ID : P30 DA029926
Pays : United States
Organisme : NIDA NIH HHS
ID : UG1 DA049435
Pays : United States
Organisme : NIDA NIH HHS
ID : T32 DA037202
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest LAM is affiliated with Pear Therapeutics, HealthSim, LLC, and Square2 Systems, Inc. Conflicts of interest are extensively managed by her academic institution, Dartmouth College.
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