Cough reflex sensitivity and urge-to-cough deterioration in dementia with Lewy bodies.
Journal
ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
29
04
2019
accepted:
03
12
2019
entrez:
14
3
2020
pubmed:
14
3
2020
medline:
14
3
2020
Statut:
epublish
Résumé
Cough, an important respiratory symptom, predominantly involves the brainstem and the urge-to-cough (UTC) is modulated by the cerebral cortex. Lewy body disease is associated with decreased cough reflex sensitivity and central respiratory chemosensitivity. Additionally, the insula, associated with the UTC, shows decreased activation and atrophy in dementia with Lewy bodies (DLB). We investigated the relationships between cognition and cough reflex and the UTC and compared the differences in responses of patients with DLB and other dementia subtypes. We conducted a cross-sectional study within a geriatric ward of a university hospital involving elderly patients diagnosed with Alzheimer's disease (AD), DLB, or non-dementia (controls). The cough reflex sensitivities were estimated based on the lowest concentrations of inhaled citric acid that could induce ≥2 coughs (C
Identifiants
pubmed: 32166090
doi: 10.1183/23120541.00108-2019
pii: 00108-2019
pmc: PMC7061205
pii:
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright ©ERS 2020.
Déclaration de conflit d'intérêts
Conflict of interest: T. Ebihara has nothing to disclose. Conflict of interest: P. Gui has nothing to disclose. Conflict of interest: C. Ooyama has nothing to disclose. Conflict of interest: K. Kozaki has nothing to disclose. Conflict of interest: S. Ebihara has nothing to disclose.
Références
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
Cough. 2008 Nov 19;4:11
pubmed: 19019213
Cancer. 1950 Jan;3(1):32-5
pubmed: 15405679
Ann Neurol. 2009 May;65(5):614-7
pubmed: 19475659
Chest. 2014 Jul;146(1):135-141
pubmed: 24556807
Lancet. 2000 Aug 26;356(9231):739-40
pubmed: 11085699
Chest. 2014 Dec;146(6):1633-1648
pubmed: 25188530
Am J Respir Crit Care Med. 1996 Feb;153(2):812-9
pubmed: 8564137
Am J Respir Crit Care Med. 2013 Nov 1;188(9):1069-75
pubmed: 24093551
BMC Geriatr. 2012 Aug 13;12:45
pubmed: 22889350
Lancet. 1990 May 19;335(8699):1228-9
pubmed: 1971077
Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R37-46
pubmed: 17008453
Sleep. 2014 Feb 01;37(2):373-8
pubmed: 24501436
Alzheimers Res Ther. 2016 Jul 12;8:29
pubmed: 27401267
Cough. 2011 Jun 28;7(1):3
pubmed: 21711545
N Engl J Med. 2009 Oct 15;361(16):1529-38
pubmed: 19828530
J Neurosci. 2011 Feb 23;31(8):2948-58
pubmed: 21414916
PLoS One. 2014 Dec 29;9(12):e116123
pubmed: 25546308
Int Psychogeriatr. 1992;4 Suppl 1:55-69
pubmed: 1504288
Chest. 2014 Nov;146(5):1294-1299
pubmed: 24968148
J Am Geriatr Soc. 2004 Apr;52(4):645-6
pubmed: 15066090
Eur Respir J. 2014 Nov;44(5):1149-55
pubmed: 25186267
Lung. 2008;186 Suppl 1:S107-11
pubmed: 17952695
Chest. 2003 Sep;124(3):1009-15
pubmed: 12970031
Neurology. 2005 Dec 27;65(12):1863-72
pubmed: 16237129
Neurology. 1996 Nov;47(5):1113-24
pubmed: 8909416
Neurology. 1984 Jul;34(7):939-44
pubmed: 6610841
Am J Respir Crit Care Med. 2002 Oct 1;166(7):961-4
pubmed: 12359654
Behav Res Methods. 2007 May;39(2):175-91
pubmed: 17695343
J Am Geriatr Soc. 2001 Jan;49(1):85-90
pubmed: 11207848
Eur J Pain. 2000;4(3):267-74
pubmed: 10985870
Psychogeriatrics. 2016 Sep;16(5):305-14
pubmed: 26510708
Chest. 2010 Nov;138(5):1166-72
pubmed: 20847041
Neurosci Lett. 2005 Jul 15;382(3):269-74
pubmed: 15925102
Sci Rep. 2017 Aug 25;7(1):9437
pubmed: 28842567