Dynamic Expression of Interleukin-33 and ST2 in the Mouse Reproductive Tract Is Influenced by Superovulation.


Journal

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
ISSN: 1551-5044
Titre abrégé: J Histochem Cytochem
Pays: United States
ID NLM: 9815334

Informations de publication

Date de publication:
04 2020
Historique:
pubmed: 29 2 2020
medline: 15 12 2020
entrez: 29 2 2020
Statut: ppublish

Résumé

Interleukin-33 (IL-33) is an IL-1 family cytokine with pleiotropic effects on diverse cell types. Dysregulated IL-33 signaling has been implicated in pregnancy-related disorders, including preeclampsia and recurrent pregnancy loss, and in ovarian function in women undergoing controlled ovarian stimulation for in vitro fertilization. To date, expression of IL-33 and its receptor subunit, ST2, in the female reproductive tract remains poorly characterized. We identify IL-33-expressing oocytes surrounded by ST2-expressing granulosa cells at all stages of follicular development, in addition to IL-33

Identifiants

pubmed: 32108542
doi: 10.1369/0022155420911049
pmc: PMC7132822
doi:

Substances chimiques

Il1rl1 protein, mouse 0
Il33 protein, mouse 0
Interleukin-1 Receptor-Like 1 Protein 0
Interleukin-33 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

253-267

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI148695
Pays : United States

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Auteurs

Salma Begum (S)

Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.

Barry E Perlman (BE)

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.

Nuriban Valero-Pacheco (N)

Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers Biomedical and Health Sciences, Newark, NJ.

Valerie O'Besso (V)

Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.

Tracy Wu (T)

Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.

Sara S Morelli (SS)

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.

Aimee M Beaulieu (AM)

Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers Biomedical and Health Sciences, Newark, NJ.
Center for Immunity and Inflammation, Rutgers Biomedical and Health Sciences, Newark, NJ.

Nataki C Douglas (NC)

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Women's Health, Rutgers Biomedical and Health Sciences, Newark, NJ.
Center for Immunity and Inflammation, Rutgers Biomedical and Health Sciences, Newark, NJ.

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Classifications MeSH