MRI Relaxivity Changes of the Magnetic Nanoparticles Induced by Different Amino Acid Coatings.
MRI
amino acid
functionalisation
glycine
lysine
maghemite
magnetic nanoparticles
relaxivity
tryptophan
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
24 Feb 2020
24 Feb 2020
Historique:
received:
30
12
2019
revised:
15
02
2020
accepted:
18
02
2020
entrez:
28
2
2020
pubmed:
28
2
2020
medline:
28
2
2020
Statut:
epublish
Résumé
In this study, we analysed the physico-chemical properties of positively charged magnetic fluids consisting of magnetic nanoparticles (MNPs) functionalised by different amino acids (AAs): glycine (Gly), lysine (Lys) and tryptophan (Trp), and the influence of AA-MNP complexes on the MRI relaxivity. We found that the AA coating affects the size of dispersed particles and isoelectric point, as well as the zeta potential of AA-MNPs differently, depending on the AA selected. Moreover, we showed that a change in hydrodynamic diameter results in a change to the relaxivity of AA-MNP complexes. On the one hand, we observed a decrease in the relaxivity values,
Identifiants
pubmed: 32102280
pii: nano10020394
doi: 10.3390/nano10020394
pmc: PMC7075310
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Competence Center Martin
ID : ITMS code: 26220220153
Organisme : Ministry of Health of the Slovak Republic
ID : 2018/11-UKMT-7
Organisme : National Grant Agency VEGA
ID : 2/0033/19
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