Advances in prostate specific antigen biosensors-impact of nanotechnology.
Aptasensor
Immunosensing
Nanomaterials
Peptide-based biosensor
Prostate specific antigen
Journal
Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
Titre abrégé: Clin Chim Acta
Pays: Netherlands
ID NLM: 1302422
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
03
12
2019
revised:
25
01
2020
accepted:
27
01
2020
pubmed:
1
2
2020
medline:
22
6
2021
entrez:
1
2
2020
Statut:
ppublish
Résumé
Prostate cancer is one of the most dangerous and deadly cancers in elderly men. Early diagnosis using prostate-specific antigen (PSA) facilitates disease detection, management and treatment. Biosensors have recently been used as sensitive, selective, inexpensive and rapid diagnostic tools for PSA detection. In this review, a variety of PSA biosensors such as aptasensors, peptisensors and immunesensors are highlighted. These use aptamers, peptides and antibodies in the biorecognition element, respectively, and can detect PSA with very high sensitivity via electrochemical, electrochemiluminescence, fluorescence and surface-enhanced Raman spectroscopy. To improve the sensitivity of most of these PSA biosensors, different nanostructured materials have played a critical role.
Identifiants
pubmed: 32004532
pii: S0009-8981(20)30048-6
doi: 10.1016/j.cca.2020.01.028
pii:
doi:
Substances chimiques
Prostate-Specific Antigen
EC 3.4.21.77
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
43-55Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.