New aromatic 6-substituted 2'-deoxy-9-(β)-d-ribofuranosylpurine derivatives as potential plant growth regulators.


Journal

Bioorganic & medicinal chemistry
ISSN: 1464-3391
Titre abrégé: Bioorg Med Chem
Pays: England
ID NLM: 9413298

Informations de publication

Date de publication:
15 01 2020
Historique:
received: 10 10 2019
accepted: 19 11 2019
pubmed: 22 12 2019
medline: 28 1 2021
entrez: 22 12 2019
Statut: ppublish

Résumé

Cytokinins are naturally occurring substances that act as plant growth regulators promoting plant growth and development, including shoot initiation and branching, and also affecting apical dominance and leaf senescence. Aromatic cytokinin 6-benzylaminopurine (BAP) has been widely used in micropropagation systems and biotechnology. However, its 9-glucoside (BAP9G) accumulates in explants, causing root inhibition and growth heterogenity. To overcome BAP disadvantages, a series of ring-substituted 2'-deoxy-9-(β)-d-ribofuranosylpurine derivatives was prepared and examined in different classical cytokinin bioassays. Amaranthus, senescence and tobacco callus bioassays were employed to provide details of cytokinin activity of 2'-deoxy-9-(β)-d-ribosides compared to their respective free bases and ribosides. The prepared derivatives were also tested for their recognition by cytokinin receptors of Arabidopsis thaliana AHK3 and CRE1/AHK4. The ability of aromatic N

Identifiants

pubmed: 31862308
pii: S0968-0896(19)31730-4
doi: 10.1016/j.bmc.2019.115230
pii:
doi:

Substances chimiques

Antioxidants 0
Plant Growth Regulators 0
Purine Nucleosides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

115230

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Vlasta Matušková (V)

Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. Electronic address: matuskova.vlasta@gmail.com.

Marek Zatloukal (M)

Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

Jiří Voller (J)

Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

Jiří Grúz (J)

Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

Zuzana Pěkná (Z)

Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

Katarína Briestenská (K)

Comenius University, Faculty of Natural Sciences, Department of Microbiology and Virology, Mlynská dolina, Ilkovičova 6, 842 15 Bratislava 4, Slovak Republic; Institute of Virology, Biomedical Center SAS, Dúbravská cesta 9, 845 05 Bratislava, Slovak Republic.

Jela Mistríková (J)

Comenius University, Faculty of Natural Sciences, Department of Microbiology and Virology, Mlynská dolina, Ilkovičova 6, 842 15 Bratislava 4, Slovak Republic; Institute of Virology, Biomedical Center SAS, Dúbravská cesta 9, 845 05 Bratislava, Slovak Republic.

Lukáš Spíchal (L)

Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

Karel Doležal (K)

Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic; Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic. Electronic address: karel.dolezal@upol.cz.

Miroslav Strnad (M)

Laboratory of Growth Regulators, The Czech Academy of Sciences, Institute of Experimental Botany & Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.

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