Blue-Light Photocleavable Protecting Groups Based on Benzothiadiazole Scaffolds.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
03 01 2020
03 01 2020
Historique:
pubmed:
18
12
2019
medline:
18
12
2019
entrez:
18
12
2019
Statut:
ppublish
Résumé
An unexpected nucleophilic aromatic substitution lead to a novel benzothiadiazole scaffold that bore the functional group pattern associated with benzyl-type photocleavable protecting groups. The new molecules display efficient photochemical release of leaving groups with blue light. The performance of both ortho- and meta-substituted derivatives was probed through both structural manipulation and computational metrics to improve performance.
Identifiants
pubmed: 31846343
doi: 10.1021/acs.orglett.9b04268
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM