Chronic nail biting, orthodontic treatment and Enterobacteriaceae in the oral cavity.


Journal

Journal of clinical and experimental dentistry
ISSN: 1989-5488
Titre abrégé: J Clin Exp Dent
Pays: Spain
ID NLM: 101603132

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 08 07 2019
accepted: 04 11 2019
entrez: 12 12 2019
pubmed: 12 12 2019
medline: 12 12 2019
Statut: epublish

Résumé

Chronic nail biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic nail-biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic nail-biting habit and or those undergoing orthodontic treatment. 150 children (no nail-biting n=30, nail biting n=60, fixed orthodontic treatment n =30 and a combination of fixed orthodontic appliance use and nail-biting habit n =30) were assessed for culture based microbiological investigation. The concentrated oral rinse technique was used. The rinse was inoculated in MacConkey's and Blood Agar. The gram stained culture was subjected to biochemical tests for sub-species identification using Biomerieux Vitek 2 Compact Automated Microbiological Analyzer. Fisher's exact and Kruskal Wallis with post hoc analysis using Dunn method was performed to test association and difference between groups. Enterobacteriaceae was positive for 72% of the children. Of them, nail biting or orthodontic treatment group comprised 89%. Those with a combination of nail biting and undergoing orthodontic treatment exhibited highest CFU/ml and those without nail biting or orthodontic treatment exhibited the lowest. Three of the four organisms isolated tested positive in the orthodontic treatment group. Chronic nail biting or the use of fixed orthodontic appliances is associated with higher incidence of Enterobacteriaceae in the oral cavity. Oral health professionals play an important role in preventing multi drug resistance infectious diseases.

Sections du résumé

BACKGROUND BACKGROUND
Chronic nail biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic nail-biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic nail-biting habit and or those undergoing orthodontic treatment.
MATERIAL AND METHODS METHODS
150 children (no nail-biting n=30, nail biting n=60, fixed orthodontic treatment n =30 and a combination of fixed orthodontic appliance use and nail-biting habit n =30) were assessed for culture based microbiological investigation. The concentrated oral rinse technique was used. The rinse was inoculated in MacConkey's and Blood Agar. The gram stained culture was subjected to biochemical tests for sub-species identification using Biomerieux Vitek 2 Compact Automated Microbiological Analyzer. Fisher's exact and Kruskal Wallis with post hoc analysis using Dunn method was performed to test association and difference between groups.
RESULTS RESULTS
Enterobacteriaceae was positive for 72% of the children. Of them, nail biting or orthodontic treatment group comprised 89%. Those with a combination of nail biting and undergoing orthodontic treatment exhibited highest CFU/ml and those without nail biting or orthodontic treatment exhibited the lowest. Three of the four organisms isolated tested positive in the orthodontic treatment group.
CONCLUSIONS CONCLUSIONS
Chronic nail biting or the use of fixed orthodontic appliances is associated with higher incidence of Enterobacteriaceae in the oral cavity. Oral health professionals play an important role in preventing multi drug resistance infectious diseases.

Identifiants

pubmed: 31824597
doi: 10.4317/jced.56059
pii: 56059
pmc: PMC6894907
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e1157-e1162

Informations de copyright

Copyright: © 2019 Medicina Oral S.L.

Déclaration de conflit d'intérêts

Conflict of interest statement:The authors have declared that no conflict of interest exist.

Références

Emerg Infect Dis. 2015 Nov;21(11):2014-21
pubmed: 26486124
J Pediatric Infect Dis Soc. 2018 Feb 19;7(1):36-45
pubmed: 28339695
Int J Dent Hyg. 2009 May;7(2):121-5
pubmed: 19416094
Bull World Health Organ. 2019 Jul 1;97(7):486-501B
pubmed: 31258218
J Oral Pathol. 1986 Aug;15(7):386-8
pubmed: 3098945
J Dermatolog Treat. 2017 Mar;28(2):166-172
pubmed: 27387832
J Oral Maxillofac Pathol. 2013 May;17(2):163-8
pubmed: 24250072
Odontostomatol Trop. 2004 Jun;27(106):9-14
pubmed: 15536715
J Oral Microbiol. 2019 Mar 18;11(1):1586422
pubmed: 30911359
J Oral Rehabil. 2012 Feb;39(2):126-35
pubmed: 21916926
J Int Oral Health. 2014 Feb;6(1):39-43
pubmed: 24653601
Genome Biol. 2012 Jun 14;13(6):R42
pubmed: 22698087
J Oral Pathol Med. 1994 Mar;23(3):104-13
pubmed: 8021843
Int J Prosthodont. 2005 Jul-Aug;18(4):291-2
pubmed: 16052775
Methods Mol Biol. 2017;1537:127-138
pubmed: 27924591
BMC Infect Dis. 2016 Jul 25;16:359
pubmed: 27456093
N Y State Dent J. 1998 Feb;64(2):48-53
pubmed: 9542394
Biol Psychiatry. 2000 Aug 15;48(4):287-93
pubmed: 10960159
Open Dent J. 2018 Apr 30;12:331-339
pubmed: 29875885
Oral Microbiol Immunol. 2007 Feb;22(1):1-4
pubmed: 17241163
Dtsch Arztebl Int. 2019 Mar 29;116(13):213-219
pubmed: 31064642
Trends Microbiol. 2006 Sep;14(9):413-20
pubmed: 16876996
Int J Paediatr Dent. 2005 Jan;15(1):29-36
pubmed: 15663442
Pediatr Infect Dis J. 2013 Jun;32(6):636-40
pubmed: 23838732
Ann Trop Med Parasitol. 2011 Jan;105(1):57-64
pubmed: 21294949
J Clin Pediatr Dent. 2013 Spring;37(3):335-9
pubmed: 23855182
Contemp Clin Dent. 2015 Apr-Jun;6(2):211-4
pubmed: 26097357
Br Dent J. 2018 Mar 23;224(6):447-455
pubmed: 29569607
Postgrad Med. 2005 Sep;118(3):37-8, 42
pubmed: 16201307

Auteurs

Alagesan Chinnasamy (A)

Population Oral Health, Melbourne Dental School, The University of Melbourne, Australia.

Karthikeyan Ramalingam (K)

Oral Pathology and Microbiology, Surendera Dental College & Research Institute, Rajasthan, India.

Pallu Chopra (P)

Oral Pathology and Microbiology, Surendera Dental College & Research Institute, Rajasthan, India.

Vidhya Gopinath (V)

Saveetha Dental College, Chennai, India.

Gyan-Prakash Bishnoi (GP)

Oral Pathology and Microbiology, Surendera Dental College & Research Institute, Rajasthan, India.

Gurveen Chawla (G)

Oral Pathology and Microbiology, Surendera Dental College & Research Institute, Rajasthan, India.

Classifications MeSH