Ex vivo
Glutamate
Glutamine
Prenatal immune activation
Stress
Striatum
Two hit model
Journal
Schizophrenia research
ISSN: 1573-2509
Titre abrégé: Schizophr Res
Pays: Netherlands
ID NLM: 8804207
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
17
05
2019
revised:
28
09
2019
accepted:
04
11
2019
pubmed:
4
12
2019
medline:
15
6
2022
entrez:
3
12
2019
Statut:
ppublish
Résumé
Prenatal infections are environmental risk factors for neurodevelopmental disorders. In addition, traumatic experiences during adolescence in individuals exposed to infections during gestation could increase the risk of schizophrenia. It is of the most crucial importance to discover potential markers of the disease in its early stages or before its onset, so that therapeutic strategies may be implemented. In the present study, we combined a proposed two-hit model of schizophrenia-related symptoms with proton magnetic resonance spectroscopy (
Identifiants
pubmed: 31787482
pii: S0920-9964(19)30505-5
doi: 10.1016/j.schres.2019.11.007
pii:
doi:
Substances chimiques
Lipopolysaccharides
0
Glutamine
0RH81L854J
Glutamic Acid
3KX376GY7L
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
232-240Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.