Building an Otoscopic screening prototype tool using deep learning.


Journal

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
ISSN: 1916-0216
Titre abrégé: J Otolaryngol Head Neck Surg
Pays: England
ID NLM: 101479544

Informations de publication

Date de publication:
26 Nov 2019
Historique:
received: 25 07 2019
accepted: 01 11 2019
entrez: 28 11 2019
pubmed: 28 11 2019
medline: 23 6 2020
Statut: epublish

Résumé

Otologic diseases are often difficult to diagnose accurately for primary care providers. Deep learning methods have been applied with great success in many areas of medicine, often outperforming well trained human observers. The aim of this work was to develop and evaluate an automatic software prototype to identify otologic abnormalities using a deep convolutional neural network. A database of 734 unique otoscopic images of various ear pathologies, including 63 cerumen impactions, 120 tympanostomy tubes, and 346 normal tympanic membranes were acquired. 80% of the images were used for the training of a convolutional neural network and the remaining 20% were used for algorithm validation. Image augmentation was employed on the training dataset to increase the number of training images. The general network architecture consisted of three convolutional layers plus batch normalization and dropout layers to avoid over fitting. The validation based on 45 datasets not used for model training revealed that the proposed deep convolutional neural network is capable of identifying and differentiating between normal tympanic membranes, tympanostomy tubes, and cerumen impactions with an overall accuracy of 84.4%. Our study shows that deep convolutional neural networks hold immense potential as a diagnostic adjunct for otologic disease management.

Sections du résumé

BACKGROUND BACKGROUND
Otologic diseases are often difficult to diagnose accurately for primary care providers. Deep learning methods have been applied with great success in many areas of medicine, often outperforming well trained human observers. The aim of this work was to develop and evaluate an automatic software prototype to identify otologic abnormalities using a deep convolutional neural network.
MATERIAL AND METHODS METHODS
A database of 734 unique otoscopic images of various ear pathologies, including 63 cerumen impactions, 120 tympanostomy tubes, and 346 normal tympanic membranes were acquired. 80% of the images were used for the training of a convolutional neural network and the remaining 20% were used for algorithm validation. Image augmentation was employed on the training dataset to increase the number of training images. The general network architecture consisted of three convolutional layers plus batch normalization and dropout layers to avoid over fitting.
RESULTS RESULTS
The validation based on 45 datasets not used for model training revealed that the proposed deep convolutional neural network is capable of identifying and differentiating between normal tympanic membranes, tympanostomy tubes, and cerumen impactions with an overall accuracy of 84.4%.
CONCLUSION CONCLUSIONS
Our study shows that deep convolutional neural networks hold immense potential as a diagnostic adjunct for otologic disease management.

Identifiants

pubmed: 31771647
doi: 10.1186/s40463-019-0389-9
pii: 10.1186/s40463-019-0389-9
pmc: PMC6880418
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

66

Références

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Auteurs

Devon Livingstone (D)

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Calgary, 7th floor, 4448 Front Street SE, Calgary, Alberta, T3M 1M4, Canada. dmliving@ucalgary.ca.

Aron S Talai (AS)

Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada.

Justin Chau (J)

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Calgary, 7th floor, 4448 Front Street SE, Calgary, Alberta, T3M 1M4, Canada.

Nils D Forkert (ND)

Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada.

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Classifications MeSH