Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line.
Adaptor Proteins, Signal Transducing
/ deficiency
Angiotensin II
/ pharmacology
Biomarkers
/ metabolism
Cell Line
Cell Line, Transformed
Clone Cells
Epithelial Cells
/ metabolism
Gene Expression Regulation
/ drug effects
Humans
Kidney Tubules, Distal
/ metabolism
RNA, Messenger
/ genetics
Receptor, Angiotensin, Type 1
/ genetics
Sirtuin 1
/ genetics
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
12 11 2019
12 11 2019
Historique:
received:
28
05
2019
accepted:
17
10
2019
entrez:
14
11
2019
pubmed:
14
11
2019
medline:
30
10
2020
Statut:
epublish
Résumé
The proximal tubule is a particularly important site for ageing-related kidney damage. Sirtuin 1 (SIRT1), an NAD
Identifiants
pubmed: 31719572
doi: 10.1038/s41598-019-52566-y
pii: 10.1038/s41598-019-52566-y
pmc: PMC6851135
doi:
Substances chimiques
AGTRAP protein, human
0
Adaptor Proteins, Signal Transducing
0
Biomarkers
0
RNA, Messenger
0
Receptor, Angiotensin, Type 1
0
Angiotensin II
11128-99-7
Sirtuin 1
EC 3.5.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
16550Références
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