Investigating combined toxicity of binary mixtures in bees: Meta-analysis of laboratory tests, modelling, mechanistic basis and implications for risk assessment.
Bees
Interactions
Laboratory toxicity
Mixtures
Pesticides
Risk assessment
Journal
Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
14
06
2019
revised:
03
10
2019
accepted:
09
10
2019
pubmed:
5
11
2019
medline:
23
2
2020
entrez:
5
11
2019
Statut:
ppublish
Résumé
Bees are exposed to a wide range of multiple chemicals "chemical mixtures" from anthropogenic (e.g. plant protection products or veterinary products) or natural origin (e.g. mycotoxins, plant toxins). Quantifying the relative impact of multiple chemicals on bee health compared with other environmental stressors (e.g. varroa, viruses, and nutrition) has been identified as a priority to support the development of holistic risk assessment methods. Here, extensive literature searches and data collection of available laboratory studies on combined toxicity data for binary mixtures of pesticides and non-chemical stressors has been performed for honey bees (Apis mellifera), wild bees (Bombus spp.) and solitary bee species (Osmia spp.). From 957 screened publications, 14 publications provided 218 binary mixture toxicity data mostly for acute mortality (lethal dose: LD
Identifiants
pubmed: 31683157
pii: S0160-4120(19)32026-4
doi: 10.1016/j.envint.2019.105256
pii:
doi:
Substances chimiques
Fungicides, Industrial
0
Pesticides
0
Types de publication
Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
105256Subventions
Organisme : Medical Research Council
ID : MR/M009157/1
Pays : United Kingdom
Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.