Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats.
cannabidiol
hypoxia-ischemia
myelin
newborn
rat
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2019
2019
Historique:
received:
01
04
2019
accepted:
30
08
2019
entrez:
16
10
2019
pubmed:
16
10
2019
medline:
16
10
2019
Statut:
epublish
Résumé
Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects neurons and glial cells after HI insult in newborn animals. We hereby aimed to study CBD's effects on long-lasting HI-induced myelination deficits in newborn rats. Thus, P7 Wistar rats received s.c. vehicle (HV) or cannabidiol (HC) after HI brain damage (left carotid artery electrocoagulation plus 10% O
Identifiants
pubmed: 31611802
doi: 10.3389/fphar.2019.01131
pmc: PMC6775595
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1131Informations de copyright
Copyright © 2019 Ceprián, Vargas, García-Toscano, Penna, Jiménez-Sánchez, Achicallende, Elezgarai, Grandes, Hind, Pazos and Martínez-Orgado.
Références
PLoS One. 2012;7(5):e36422
pubmed: 22567156
Free Radic Biol Med. 2011 May 15;50(10):1368-81
pubmed: 21362471
J Cereb Blood Flow Metab. 2010 May;30(5):1053-65
pubmed: 20068573
Clin Perinatol. 2009 Dec;36(4):835-58, vii
pubmed: 19944838
Nat Rev Neurol. 2015 Apr;11(4):192-208
pubmed: 25686754
Clin Perinatol. 2014 Mar;41(1):1-24
pubmed: 24524444
Neurology. 2011 Jun 14;76(24):2055-61
pubmed: 21670434
J Neurochem. 2011 Jan;116(1):53-66
pubmed: 21044081
Glia. 2013 May;61(5):732-49
pubmed: 23440860
J Neuroimmune Pharmacol. 2013 Mar;8(1):66-78
pubmed: 22367679
Brain Pathol. 2008 Jul;18(3):387-400
pubmed: 18371179
Front Neurosci. 2016 Jul 12;10:323
pubmed: 27462203
Semin Fetal Neonatal Med. 2017 Jun;22(3):153-160
pubmed: 28238633
Pediatr Res. 2008 Dec;64(6):653-8
pubmed: 18679164
Neuropharmacology. 2012 Oct;63(5):776-83
pubmed: 22659086
Neuropharmacology. 2017 Apr;116:151-159
pubmed: 28012949
J Neurochem. 2004 Jul;90(2):392-404
pubmed: 15228596
Pediatr Res. 2011 Sep;70(3):272-7
pubmed: 21654550
Nat Neurosci. 2013 Sep;16(9):1211-1218
pubmed: 23872599
Arch Dis Child Fetal Neonatal Ed. 2010 May;95(3):F220-4
pubmed: 20444814
Brain Dev. 2017 Feb;39(2):107-111
pubmed: 27697304
Nature. 2005 Dec 22;438(7071):1167-71
pubmed: 16372012
J Cereb Blood Flow Metab. 2007 Feb;27(2):334-47
pubmed: 16757980
Neurotox Res. 2014 Nov;26(4):307-16
pubmed: 24532152
Int J Dev Neurosci. 2002 Nov;20(7):555-62
pubmed: 12485623
Ann Neurol. 2012 Jan;71(1):93-109
pubmed: 22275256
Eur Rev Med Pharmacol Sci. 2015 Dec;19(24):4906-19
pubmed: 26744883
Neurosci Biobehav Rev. 2007;31(5):673-704
pubmed: 17368764
J Neurosci Res. 2004 Jun 15;76(6):834-45
pubmed: 15160395
J Neurosci. 2004 May 5;24(18):4412-20
pubmed: 15128855
Neuroscience. 2015 Apr 2;290:279-87
pubmed: 25637488
Nat Commun. 2016 Mar 09;7:10883
pubmed: 26955760
Pediatr Res. 2011 Jan;69(1):51-5
pubmed: 20856166
Semin Pediatr Neurol. 2009 Dec;16(4):167-78
pubmed: 19945651
Mol Neurobiol. 2018 May;55(5):4388-4402
pubmed: 28660484
Ann Neurol. 2008 Apr;63(4):520-30
pubmed: 18393269
Neuropharmacology. 2013 Aug;71:282-91
pubmed: 23587650
Mcgill J Med. 2006 Jul;9(2):134-40
pubmed: 18523615
Stroke. 2010 May;41(5):1032-7
pubmed: 20360553
Glia. 2014 Nov;62(11):1790-815
pubmed: 24687630
J Clin Pharmacol. 2002 Nov;42(S1):11S-19S
pubmed: 12412831
Exp Neurol. 2013 Sep;247:720-9
pubmed: 23524193
Br J Pharmacol. 2015 Jul;172(14):3579-95
pubmed: 25857324
Nat Commun. 2015 Aug 25;6:8073
pubmed: 26305015
Pediatr Res. 2011 Jan;69(1):56-61
pubmed: 20856165
J Neurosci. 2009 May 13;29(19):6196-206
pubmed: 19439597
Cereb Cortex. 2015 Feb;25(2):482-95
pubmed: 24046081
Early Hum Dev. 2010 Jun;86(6):329-38
pubmed: 20554402
J Neurosci. 2002 Jul 15;22(14):5910-9
pubmed: 12122053
J Psychiatry Neurosci. 2010 Jan;35(1):20-32
pubmed: 20040243
Cell Death Dis. 2012 Jun 28;3:e331
pubmed: 22739983
J Neurosci. 2002 Jan 15;22(2):455-63
pubmed: 11784790
Ann Neurol. 2012 Dec;72(6):936-51
pubmed: 23280842
Pediatr Res. 2002 Jan;51(1):25-33
pubmed: 11756636
Front Cell Neurosci. 2014 Jul 28;8:201
pubmed: 25120430
Pediatr Res. 2013 Dec;74 Suppl 1:50-72
pubmed: 24366463
Ann Neurol. 2011 Oct;70(4):525-9
pubmed: 22028217
J Neuropathol Exp Neurol. 2002 Feb;61(2):197-211
pubmed: 11853021
Ann Neurol. 2012 Aug;72(2):156-66
pubmed: 22926849