Left atrial anteroposterior diameter in dogs: reference interval, allometric scaling, and agreement with the left atrial-to-aortic root ratio.
canine
cardiology
degenerative valvular disease
echocardiography
myxomatous mitral valve disease
Journal
The Journal of veterinary medical science
ISSN: 1347-7439
Titre abrégé: J Vet Med Sci
Pays: Japan
ID NLM: 9105360
Informations de publication
Date de publication:
05 Dec 2019
05 Dec 2019
Historique:
pubmed:
16
10
2019
medline:
14
4
2020
entrez:
16
10
2019
Statut:
ppublish
Résumé
Left atrial enlargement (LAE) is a well-known negative prognostic factor in dogs with myxomatous mitral valve disease (MMVD). Left atrial-to-aortic root ratio (LA/Ao) is the most commonly used method to evaluate left atrial (LA) size in dogs, while the left atrial anteroposterior diameter (LAD) has been proposed as an additional measurement of LA size in different species. The aim of this study was to establish a normal reference range of LAD normalized to body weight (LADn) in dogs using allometric scales, and to evaluate the agreement between LADn and LA/Ao in the detection of LAE in dogs with MMVD. This was a retrospective, multicenter, observational study. We included 330 healthy dogs, 30 dogs with MMVD in ACVIM stage B1, 30 dogs in ACVIM stage B2, and 30 dogs in ACVIM stage C. The reference range for the LAD, depending on body weight, was between 16.91 mm and 49.68 mm. The reference range for the LADn in healthy dogs was between 10.49 and 15.72. LADn was significantly greater in dogs with MMVD compared to healthy dogs, and a significant difference in LADn was noted between different ACVIM stages (P<0.001). The most accurate cut-off value of LADn to differentiate between dogs in groups B2 and C was 20.3 (sensitivity, 83.3%; specificity, 83.3%). There was a misclassification rate of 37% between LADn and LA/Ao in the detection of LAE in group B1. This study provides a normal reference range for LAD in dogs, which can be used as an additional tool to assess LAE in dogs with MMVD.
Identifiants
pubmed: 31611490
doi: 10.1292/jvms.19-0240
pmc: PMC6895628
doi:
Types de publication
Journal Article
Multicenter Study
Observational Study, Veterinary
Langues
eng
Sous-ensembles de citation
IM
Pagination
1655-1662Références
Vet Radiol Ultrasound. 2002 Nov-Dec;43(6):568-75
pubmed: 12502113
J Vet Intern Med. 2004 May-Jun;18(3):311-21
pubmed: 15188817
J Vet Intern Med. 2000 Jul-Aug;14(4):429-35
pubmed: 10935894
J Vet Intern Med. 2016 Jul;30(4):1241-52
pubmed: 27362277
J Vet Intern Med. 2008 Jul-Aug;22(4):924-30
pubmed: 18537876
Vet Clin North Am Small Anim Pract. 1985 Nov;15(6):1177-94
pubmed: 3878617
J Vet Intern Med. 2008 Jan-Feb;22(1):120-8
pubmed: 18289298
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70
pubmed: 25712077
J Vet Intern Med. 2016 Nov;30(6):1765-1779
pubmed: 27678080
J Vet Cardiol. 2012 Mar;14(1):127-48
pubmed: 22366573
J Vet Cardiol. 2015 Mar;17(1):1-12
pubmed: 25586168
Heart. 2001 Mar;85(3):272-7
pubmed: 11179264
J Vet Intern Med. 2011 Nov-Dec;25(6):1320-7
pubmed: 22092623
Res Vet Sci. 2009 Apr;86(2):325-31
pubmed: 18799175
J Vet Intern Med. 2011 Sep-Oct;25(5):1025-35
pubmed: 21848966
J Am Soc Echocardiogr. 2008 Jul;21(7):779-85
pubmed: 18329846
J Vet Cardiol. 2015 Dec;17 Suppl 1:S282-95
pubmed: 26776586
Eur J Echocardiogr. 2003 Mar;4(1):36-42
pubmed: 12565061
Am Heart J. 2008 Dec;156(6):1056-64
pubmed: 19032999
J Small Anim Pract. 2012 Jan;53(1):27-33
pubmed: 22098095
J Vet Cardiol. 2019 Jun;23:58-68
pubmed: 31174730
J Vet Cardiol. 2016 Jun;18(2):137-45
pubmed: 27009978
J Vet Med Sci. 2017 Nov 10;79(11):1764-1771
pubmed: 28993567
J Vet Cardiol. 2018 Oct;20(5):330-342
pubmed: 30143416
Vet J. 2013 Sep;197(3):639-45
pubmed: 23838204
J Vet Intern Med. 2019 May;33(3):1127-1140
pubmed: 30974015
J Vet Cardiol. 2016 Mar;18(1):15-25
pubmed: 26810488
J Am Soc Echocardiogr. 2002 Feb;15(2):167-84
pubmed: 11836492
J Vet Cardiol. 2016 Dec;18(4):336-349
pubmed: 27538535
J Vet Intern Med. 2003 Sep-Oct;17(5):653-62
pubmed: 14529131
J Vet Intern Med. 2006 Jan-Feb;20(1):111-9
pubmed: 16496930
J Vet Intern Med. 1993 Jul-Aug;7(4):247-52
pubmed: 8246215
Vet Clin North Am Small Anim Pract. 2010 Jul;40(4):651-63
pubmed: 20610017
J Vet Intern Med. 2008 Sep-Oct;22(5):1124-35
pubmed: 18638016