Going in Circles: The Black Box of Circular RNA Immunogenicity.

Adenosine / analogs & derivatives RNA RNA Splicing RNA, Circular

Journal

Molecular cell
ISSN: 1097-4164
Titre abrégé: Mol Cell
Pays: United States
ID NLM: 9802571

Informations de publication

Date de publication:
03 10 2019
Historique:
entrez: 5 10 2019
pubmed: 5 10 2019
medline: 11 2 2020
Statut: ppublish

Résumé

Two recent papers in Molecular Cell (Chen et al., 2019; Wesselhoeft et al., 2019) have probed the putative immunogenicity of circular RNAs (circRNAs). These studies indicate that the stimulatory capacity of circRNAs depends on factors including the specific RNA, the mode of biogenesis, RNA modifications, cell type, and the means of delivery.

Identifiants

DOI: 10.1016/j.molcel.2019.08.027 PMID: 31585102
pubmed: 31585102
pii: S1097-2765(19)30682-3
doi: 10.1016/j.molcel.2019.08.027
pii:
doi:

Substances chimiques

RNA, Circular 0
RNA 63231-63-0
N-methyladenosine CLE6G00625
Adenosine K72T3FS567

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

3-5

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

Auteurs

Megha G Basavappa (MG)

Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Sara Cherry (S)

Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: cherrys@pennmedicine.upenn.edu.

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Classifications MeSH

Recherchemedicale.com › Acides nucléiques, nucléotides et nucléosides › Nucléosides › Ribonucléosides › Adénosine › Going in Circles: The Black Box of Circular...
Recherchemedicale.com › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › Going in Circles: The Black Box of Circular...
Recherchemedicale.com › Phénomènes génétiques › Régulation de l'expression des gènes › Maturation post-transcriptionnelle des ARN › Épissage des ARN › Going in Circles: The Black Box of Circular...
Recherchemedicale.com › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN circulaire › Going in Circles: The Black Box of Circular...