Occurrence of and risk factors for extended-spectrum cephalosporin-resistant Enterobacteriaceae determined by sampling of all Norwegian broiler flocks during a six month period.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 25 06 2019
accepted: 12 09 2019
entrez: 27 9 2019
pubmed: 27 9 2019
medline: 3 4 2020
Statut: epublish

Résumé

All broiler flocks reared and slaughtered in Norway from May-October 2016 (n = 2110) were screened for the presence of extended-spectrum cephalosporin (ESC) -resistant Enterobacteriaceae. Furthermore, we investigated possible risk factors for occurrence of such bacteria in broiler flocks. The odds of a flock being positive for ESC-resistant Enterobacteriaceae increased if the previous flock in the same house was positive, and if the flock was reared during September-October. However, we cannot exclude seasonal fluctuations in occurrence of ESC-resistant Enterobacteriaceae during the months November to April. The overall occurrence of ESC-resistant Enterobacteriaceae was 10.4%, and primarily linked to the presence of blaCMY (82.6%) in positive isolates. We describe the first findings of Escherichia coli with blaCTX-M-1, Klebsiella pneumoniae with both blaCTX-M-15 and blaSHV-12, and K. pneumoniae with blaCMY isolated from Norwegian broiler production. This study gives us a unique overview and estimate of the true occurrence of ESC-resistant Enterobacteriaceae in Norwegian broilers over a six-month period. To the best of our knowledge, this is the most comprehensive study performed on the occurrence of ESC-resistant Enterobacteriaceae in a broiler population.

Identifiants

pubmed: 31557254
doi: 10.1371/journal.pone.0223074
pii: PONE-D-19-17918
pmc: PMC6762140
doi:

Substances chimiques

Anti-Bacterial Agents 0
Cephalosporins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0223074

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Solveig Sølverød Mo (SS)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Anne Margrete Urdahl (AM)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Live Lingaas Nesse (LL)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Jannice Schau Slettemeås (JS)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Silje Nøstvedt Ramstad (SN)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Mona Torp (M)

Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Oslo, Norway.

Madelaine Norström (M)

Department of Analysis and Diagnostics, Norwegian Veterinary Institute, Oslo, Norway.

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