Directed Networks as a Novel Way to Describe and Analyze Cardiac Excitation: Directed Graph Mapping.

atrial tachycardia cardiac arrhythmia focal activity network theory phase mapping rotational activity

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2019
Historique:
received: 03 06 2019
accepted: 19 08 2019
entrez: 26 9 2019
pubmed: 26 9 2019
medline: 26 9 2019
Statut: epublish

Résumé

Networks provide a powerful methodology with applications in a variety of biological, technological and social systems such as analysis of brain data, social networks, internet search engine algorithms, etc. To date, directed networks have not yet been applied to characterize the excitation of the human heart. In clinical practice, cardiac excitation is recorded by multiple discrete electrodes. During (normal) sinus rhythm or during cardiac arrhythmias, successive excitation connects neighboring electrodes, resulting in their own unique directed network. This in theory makes it a perfect fit for directed network analysis. In this study, we applied directed networks to the heart in order to describe and characterize cardiac arrhythmias. Proof-of-principle was established using

Identifiants

pubmed: 31551814
doi: 10.3389/fphys.2019.01138
pmc: PMC6746922
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1138

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Auteurs

Nele Vandersickel (N)

Department of Physics and Astronomy, Ghent University, Ghent, Belgium.

Enid Van Nieuwenhuyse (E)

Department of Physics and Astronomy, Ghent University, Ghent, Belgium.

Nico Van Cleemput (N)

Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.

Jan Goedgebeur (J)

Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
Computer Science Department, University of Mons, Mons, Belgium.

Milad El Haddad (M)

Ghent University Hospital Heart Center, Ghent University, Ghent, Belgium.

Jan De Neve (J)

Department of Data Analysis, Ghent University, Ghent, Belgium.

Anthony Demolder (A)

Ghent University Hospital Heart Center, Ghent University, Ghent, Belgium.

Teresa Strisciuglio (T)

Cardiology Department, AZ Sint-Jan, Bruges, Belgium.

Mattias Duytschaever (M)

Ghent University Hospital Heart Center, Ghent University, Ghent, Belgium.
Cardiology Department, AZ Sint-Jan, Bruges, Belgium.

Alexander V Panfilov (AV)

Department of Physics and Astronomy, Ghent University, Ghent, Belgium.
Laboratory of Computational Biology and Medicine, Ural Federal University, Ekaterinburg, Russia.

Classifications MeSH