Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality.


Journal

Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691

Informations de publication

Date de publication:
17 09 2019
Historique:
received: 07 12 2018
revised: 17 04 2019
accepted: 12 07 2019
entrez: 19 9 2019
pubmed: 19 9 2019
medline: 12 9 2020
Statut: ppublish

Résumé

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including mice and humans. By sequencing RNA from sorted MR1-5-OP-RU tetramer

Identifiants

pubmed: 31533045
pii: S2211-1247(19)30936-2
doi: 10.1016/j.celrep.2019.07.039
pmc: PMC6859474
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3249-3262.e5

Subventions

Organisme : Wellcome Trust
ID : 109965/Z/15/Z
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.

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Auteurs

Timothy S C Hinks (TSC)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia; Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, OX3 9DU, Oxfordshire, UK. Electronic address: timothy.hinks@ndm.ox.ac.uk.

Emanuele Marchi (E)

Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, OX1 3SY, Oxfordshire, UK.

Maisha Jabeen (M)

Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, OX3 9DU, Oxfordshire, UK.

Moshe Olshansky (M)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia; Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

Ayako Kurioka (A)

Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, OX1 3SY, Oxfordshire, UK.

Troi J Pediongco (TJ)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

Bronwyn S Meehan (BS)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

Lyudmila Kostenko (L)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

Stephen J Turner (SJ)

Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

Alexandra J Corbett (AJ)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

Zhenjun Chen (Z)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

Paul Klenerman (P)

Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, OX1 3SY, Oxfordshire, UK; Translational Gastroenterology Unit, Level 5 John Radcliffe Hospital, OX3 9DU, Oxfordshire, UK.

James McCluskey (J)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC 3000, Australia.

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Classifications MeSH