Luminescent Nanosensors for Ratiometric Monitoring of Three-Dimensional Oxygen Gradients in Laboratory and Clinical Pseudomonas aeruginosa Biofilms.
biofilms
biosensors
cystic fibrosis
nanosensors
oxygen sensing
Journal
Applied and environmental microbiology
ISSN: 1098-5336
Titre abrégé: Appl Environ Microbiol
Pays: United States
ID NLM: 7605801
Informations de publication
Date de publication:
15 10 2019
15 10 2019
Historique:
received:
17
05
2019
accepted:
09
08
2019
pubmed:
20
8
2019
medline:
24
7
2020
entrez:
18
8
2019
Statut:
epublish
Résumé
Bacterial biofilms can form persistent infections on wounds and implanted medical devices and are associated with many chronic diseases, such as cystic fibrosis. These infections are medically difficult to treat, as biofilms are more resistant to antibiotic attack than their planktonic counterparts. An understanding of the spatial and temporal variation in the metabolism of biofilms is a critical component toward improved biofilm treatments. To this end, we developed oxygen-sensitive luminescent nanosensors to measure three-dimensional (3D) oxygen gradients, an application of which is demonstrated here with
Identifiants
pubmed: 31420335
pii: AEM.01116-19
doi: 10.1128/AEM.01116-19
pmc: PMC6805078
pii:
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NINDS NIH HHS
ID : P30 NS048154
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS086839
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001082
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Microbiology.
Références
Appl Environ Microbiol. 2007 Oct;73(19):6289-95
pubmed: 17704276
ACS Nano. 2015 Feb 24;9(2):1692-8
pubmed: 25588028
Antimicrob Agents Chemother. 2011 Sep;55(9):4469-74
pubmed: 21670181
Water Res. 2017 May 15;115:50-59
pubmed: 28259814
Anal Chem. 2017 Oct 17;89(20):11044-11052
pubmed: 28920437
Clin Pharmacokinet. 2005;44(2):201-10
pubmed: 15656698
Biomaterials. 2009 Jun;30(17):3068-74
pubmed: 19285719
Water Environ Res. 2001 May-Jun;73(3):368-73
pubmed: 11561597
Scand J Respir Dis. 1977 Apr;58(2):65-79
pubmed: 404701
Lab Chip. 2018 Jul 24;18(15):2202-2213
pubmed: 29944153
Rep Prog Phys. 2015 Feb;78(3):036601
pubmed: 25719969
Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):848-52
pubmed: 23271809
Biosens Bioelectron. 2019 Jan 1;123:131-140
pubmed: 30060990
Analyst. 2016 May 10;141(10):2887-95
pubmed: 26939806
J Clin Microbiol. 2005 Oct;43(10):5085-90
pubmed: 16207967
Appl Environ Microbiol. 2009 Nov;75(22):7189-95
pubmed: 19767473
Methods. 2008 Nov;46(3):143-51
pubmed: 18929663
Ther Adv Respir Dis. 2017 May;11(5):193-209
pubmed: 28470103
Water Res. 2011 Oct 15;45(16):5027-37
pubmed: 21803395
Infect Immun. 1980 May;28(2):546-56
pubmed: 6772562
Biotechnol Bioeng. 2017 Apr;114(4):915-923
pubmed: 27775151
Antimicrob Agents Chemother. 2003 Jan;47(1):317-23
pubmed: 12499208
Anal Chem. 2013 Jul 2;85(13):6312-8
pubmed: 23767828
Nat Rev Microbiol. 2004 Feb;2(2):95-108
pubmed: 15040259
Biotechnol Bioeng. 2012 Oct;109(10):2663-70
pubmed: 22511120
Appl Environ Microbiol. 2009 Dec;75(23):7426-35
pubmed: 19801466
Anal Chem. 2018 Feb 6;90(3):2376-2383
pubmed: 29323486
Radiat Res. 2008 Nov;170(5):651-60
pubmed: 18959466
Appl Environ Microbiol. 2016 Oct 14;82(21):6403-6413
pubmed: 27565622
J Vis Exp. 2012 Jun 05;(64):e3857
pubmed: 22711026
Adv Pediatr Infect Dis. 1993;8:53-66
pubmed: 8217005
Appl Environ Microbiol. 1997 Mar;63(3):973-7
pubmed: 16535560
J Bacteriol. 2013 Apr;195(7):1371-80
pubmed: 23292774
J Microbiol Methods. 2011 Apr;85(1):67-74
pubmed: 21277912
J Clin Invest. 2002 Feb;109(3):317-25
pubmed: 11827991
Analyst. 2018 Jan 21;143(2):458-465
pubmed: 29226289
Appl Environ Microbiol. 2017 Mar 2;83(6):
pubmed: 28062458
J Bacteriol. 2003 Mar;185(5):1485-91
pubmed: 12591863
Nat Rev Microbiol. 2008 Mar;6(3):199-210
pubmed: 18264116
Chem Rev. 2014 Jan 8;114(1):590-659
pubmed: 24024656
Chem Soc Rev. 2014 Jul 7;43(13):4563-601
pubmed: 24723011
Nature. 2000 Oct 12;407(6805):762-4
pubmed: 11048725
ACS Nano. 2016 Apr 26;10(4):4020-30
pubmed: 27089024
Clin Microbiol Infect. 2014 Oct;20(10):981-90
pubmed: 24766583
Mater Sci Eng C Mater Biol Appl. 2016 Feb;59:801-806
pubmed: 26652435
Nat Rev Microbiol. 2016 Sep;14(9):589-600
pubmed: 27452230
Biofouling. 2018 Feb;34(2):200-211
pubmed: 29405091
Soft Matter. 2017 Oct 18;13(40):7389-7397
pubmed: 28951912
Sci Total Environ. 2017 Mar 1;581-582:277-288
pubmed: 28041694
Appl Environ Microbiol. 2013 Nov;79(21):6524-34
pubmed: 23974141
Appl Environ Microbiol. 1998 Oct;64(10):4035-9
pubmed: 9758837