Hodgkin Lymphoma in an Adolescent With Isolated Bone Marrow and Bone Involvement: A Case Report and a Review of the Literature.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
01 2021
Historique:
pubmed: 16 8 2019
medline: 7 4 2021
entrez: 16 8 2019
Statut: ppublish

Résumé

Primary presentation of Hodgkin lymphoma (HL) with bone and/or bone marrow involvement is a rare entity. Diagnostic criteria, treatment approaches, and follow-up strategies for these patients have not been standardized. We report a unique case of bone and bone marrow HL in an adolescent male without lymph node involvement. It is important to keep HL in the differential diagnosis of isolated and multifocal bone lesions. Evidence is needed to define the best management of these patients.

Sections du résumé

BACKGROUND
Primary presentation of Hodgkin lymphoma (HL) with bone and/or bone marrow involvement is a rare entity. Diagnostic criteria, treatment approaches, and follow-up strategies for these patients have not been standardized.
OBSERVATION
We report a unique case of bone and bone marrow HL in an adolescent male without lymph node involvement.
CONCLUSIONS
It is important to keep HL in the differential diagnosis of isolated and multifocal bone lesions. Evidence is needed to define the best management of these patients.

Identifiants

pubmed: 31415282
doi: 10.1097/MPH.0000000000001580
pii: 00043426-202101000-00036
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e115-e118

Références

Lamba BMS, Talreja V, Sudeep V, et al. A case report of primary Hodgkin’s disease of bone marrow. Sahel Medical Journal. 2015;18:87–88.
Citow JS, Rini B, Wollmann R, et al. Isolated, primary extranodal Hodgkin’s disease of the spine: case report. Neurosurgery. 2001;49:453–456; discussion 456-7.
Mauz-Korholz C, Hasenclever D, Dorffel W, et al. Procarbazine-free OEPA-COPDAC chemotherapy in boys and standard OPPA-COPP in girls have comparable effectiveness in pediatric Hodgkin’s lymphoma: the GPOH-HD-2002 study. J Clin Oncol. 2010;28:3680–3686.
Gross SB, Robertson WW Jr, Lange BJ, et al. Primary Hodgkin’s disease of bone. A report of two cases in adolescents and review of the literature. Clin Orthop Relat Res. 1992:276–280.
Langley CR, Garrett SJ, Urand J, et al. Primary multifocal osseous Hodgkin’s lymphoma. World J Surg Oncol. 2008;6:34.
Breibach F, Julian A, Laurent C, et al. Contribution of the 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography to the diagnosis of primary osseous Hodgkin lymphoma. BMJ Case Rep. 2009;2009:bcr0820080696.
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Gopas J, Stern E, Zurgil U, et al. Reed-Sternberg cells in Hodgkin’s lymphoma present features of cellular senescence. Cell Death Dis. 2016;7:e2457–e2457.
Ostrowski ML, Inwards CY, Strickler JG, et al. Osseous Hodgkin disease. Cancer. 1999;85:1166–1178.
Spijkers S, Littooij AS, Humphries PD, et al. Imaging features of extranodal involvement in paediatric Hodgkin lymphoma. Pediatr Radio. 2018;49:266–276.

Auteurs

Jalila Alkendi (J)

Division of Hematology and Oncology.

Samuele Renzi (S)

Division of Hematology and Oncology.

David Manson (D)

Division of Radiology.

Mohamed Abdelhaleem (M)

Division of Laboratory, The Hospital for Sick Children.

Ahmed Naqvi (A)

Division of Hematology and Oncology.
Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Angela Punnett (A)

Division of Hematology and Oncology.
Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

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