A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G
Adenosine Triphosphate
/ genetics
Alanine
/ genetics
Cell Cycle Proteins
/ chemistry
Gene Expression Regulation
/ genetics
HeLa Cells
Humans
Hydrophobic and Hydrophilic Interactions
Mitochondria
/ genetics
Molecular Chaperones
/ genetics
Multiprotein Complexes
/ chemistry
Mutation
Myocardial Ischemia
/ genetics
Myocytes, Cardiac
/ metabolism
Oxidative Phosphorylation
Proteolysis
Ubiquitin-Protein Ligases
/ genetics
Ubiquitination
/ genetics
ATP
BCL2-associated athanogene 6
RING finger protein 126 (RNF126)
hypoxia
ischemic heart disease
mitochondria
protein degradation
small interfering RNA (siRNA)
ubiquitin ligase
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
04 10 2019
04 10 2019
Historique:
received:
27
03
2019
revised:
19
07
2019
pubmed:
3
8
2019
medline:
7
5
2020
entrez:
3
8
2019
Statut:
ppublish
Résumé
Oxidative phosphorylation generates most of the ATP in respiring cells. ATP is an essential energy source, especially in cardiomyocytes because of their continuous contraction and relaxation. Previously, we reported that G
Identifiants
pubmed: 31371451
pii: S0021-9258(20)35010-9
doi: 10.1074/jbc.RA119.008544
pmc: PMC6779449
doi:
Substances chimiques
BAG6 protein, human
0
Cell Cycle Proteins
0
G0S2 protein, human
0
Molecular Chaperones
0
Multiprotein Complexes
0
Adenosine Triphosphate
8L70Q75FXE
RNF126 protein, human
EC 2.3.2.27
Ubiquitin-Protein Ligases
EC 2.3.2.27
Alanine
OF5P57N2ZX
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
14562-14573Informations de copyright
© 2019 Kamikubo et al.
Références
Nature. 2011 Jul 10;475(7356):394-7
pubmed: 21743475
Cancer Res. 2013 Jan 1;73(1):385-94
pubmed: 23026136
Mol Cell. 2011 Jun 24;42(6):758-70
pubmed: 21636303
Cell Chem Biol. 2019 Feb 21;26(2):156-177
pubmed: 30554913
PLoS One. 2016 Jun 01;11(6):e0156742
pubmed: 27248498
Nat Rev Mol Cell Biol. 2008 Sep;9(9):679-90
pubmed: 18698327
J Cell Sci. 2013 Mar 15;126(Pt 6):1366-80
pubmed: 23418353
J Clin Invest. 2007 Oct;117(10):2812-24
pubmed: 17885681
Curr Biol. 2018 Apr 23;28(8):R498-R511
pubmed: 29689233
J Cell Biol. 2010 Aug 23;190(4):637-50
pubmed: 20713601
Mol Cell. 2018 Aug 2;71(3):443-457
pubmed: 30075143
Mol Cell. 2014 Jul 17;55(2):227-37
pubmed: 24981174
Science. 2001 May 25;292(5521):1552-5
pubmed: 11375494
Cell Rep. 2017 Feb 21;18(8):2007-2017
pubmed: 28228265
Cell. 2012 Feb 3;148(3):399-408
pubmed: 22304911
Cell Metab. 2006 Mar;3(3):187-97
pubmed: 16517406
Cell. 1991 Jan 11;64(1):13-5
pubmed: 1986863
J Biol Chem. 1996 Dec 20;271(51):32529-37
pubmed: 8955077
Mol Cell Biol. 2017 Feb 1;37(4):
pubmed: 27895153
Cancer Med. 2016 Aug;5(8):2043-7
pubmed: 27227488
Science. 2017 Jan 20;355(6322):298-302
pubmed: 28104892
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1553-8
pubmed: 25605899
Cell Metab. 2006 Mar;3(3):177-85
pubmed: 16517405
Nat Commun. 2016 Jan 06;7:10239
pubmed: 26732515
Cell Discov. 2016 Jul 26;2:16019
pubmed: 27462466
Sci Rep. 2017 Nov 6;7(1):14545
pubmed: 29109525
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15651-6
pubmed: 19720993
Annu Rev Biochem. 1998;67:425-79
pubmed: 9759494
Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):273-8
pubmed: 24344269