Metabolic Perturbations from Step Reduction in Older Persons at Risk for Sarcopenia: Plasma Biomarkers of Abrupt Changes in Physical Activity.
ageing
capillary electrophoresis
mass spectrometry
metabolomics
obesity
physical inactivity
sarcopenia
Journal
Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790
Informations de publication
Date de publication:
08 Jul 2019
08 Jul 2019
Historique:
received:
02
06
2019
revised:
27
06
2019
accepted:
04
07
2019
entrez:
11
7
2019
pubmed:
11
7
2019
medline:
11
7
2019
Statut:
epublish
Résumé
Sarcopenia is the age-related loss of skeletal muscle mass, strength and function, which may be accelerated during periods of physical inactivity. Declines in skeletal muscle and functionality not only impacts mobility but also increases chronic disease risk, such as type 2 diabetes. The aim of this study was to measure adaptive metabolic responses to acute changes in habitual activity in a cohort of overweight, pre-diabetic older adults (age = 69 ± 4 years; BMI = 27 ± 4 kg/m
Identifiants
pubmed: 31288431
pii: metabo9070134
doi: 10.3390/metabo9070134
pmc: PMC6680920
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : n/a
Organisme : Genome Canada
ID : n/a
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