Effects of mindfulness training on the default mode network in borderline personality disorder.
anterior insula
borderline personality disorder
default mode network
mindfulness
Journal
Clinical psychology & psychotherapy
ISSN: 1099-0879
Titre abrégé: Clin Psychol Psychother
Pays: England
ID NLM: 9416196
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
11
03
2019
accepted:
13
05
2019
pubmed:
28
5
2019
medline:
4
4
2020
entrez:
28
5
2019
Statut:
ppublish
Résumé
Patients with borderline personality disorder (BPD) present dysfunctions of the default mode network (DMN). Mindfulness training has proven effective to improve the symptoms of BPD. The present study examines the effect of mindfulness training on BPD symptomatology and DMN activity during the performance of a working memory task in patients with BPD. Sixty-five individuals with BPD were randomized to receive psychotherapy with either the mindfulness module of dialectical behavioural therapy (DBT-M) or with interpersonal effectiveness module (DBT-IE). The impact of treatments was evaluated with clinical and mindfulness variables as well as with functional magnetic resonance imaging during performance of the task. Both groups showed improvement in BPD symptoms and other clinical variables after treatment. Unexpectedly, there were no between-group differences in DMN activation or deactivation. However, activation of the left anterior insula increased in both groups after the intervention. Compared with the control group, participants in the DBT-M group presented higher deactivation in a cluster extending bilaterally from the calcarine to the cuneus and superior occipital gyri.
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
562-571Subventions
Organisme : European Regional Development Fund (ERDF)
Organisme : Instituto de Salud Carlos III
ID : PI13/00134
Organisme : Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM)
Informations de copyright
© 2019 John Wiley & Sons, Ltd.
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