Efficacy and Safety of Electroconvulsive Therapy in Adolescents: A Retrospective Chart Review Study From Turkey.


Journal

The journal of ECT
ISSN: 1533-4112
Titre abrégé: J ECT
Pays: United States
ID NLM: 9808943

Informations de publication

Date de publication:
Mar 2020
Historique:
pubmed: 17 5 2019
medline: 18 5 2021
entrez: 17 5 2019
Statut: ppublish

Résumé

The aim of this study was to report the efficacy and safety of electroconvulsive therapy (ECT) in manic, depressed, psychotic, and catatonic adolescent patients. Medical records of 78 adolescents who had received ECT in Department of Psychiatry, Gaziantep University Medical Faculty, during 2011 to 2017 were reviewed. Sixty-two subjects in this sample were identified to have complete records and met the study inclusion criteria. The mean ± SD age of subjects was 17.11 ± 1.04 years and female sex was 53.2% (n = 33). Primary the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision or the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnoses were bipolar mood disorders (n = 33, 53.2%), major depressive disorder (n = 16, 25.8%), schizophrenia (n = 8, 12.9%), and schizoaffective disorders (n = 5, 8.1%). Electroconvulsive therapy was significantly effective in treating manic, depressive, psychotic, and catatonia symptoms as evidenced by significant differences in pretreatment and posttreatment scores in outcome measures including Hamilton Depression Rating Scale, Young Mania Rating Scale, Positive and Negative Syndrome Scale, and Clinical Global Impression-Severity Scale (P < 0.001). Presence of comorbidity adversely affected treatment response (P = 0.001). However, ECT was also effective in those with comorbid diagnoses (P < 0.001). Depressive symptoms in patients with bipolar depression responded better than those with unipolar depression (P = 0.012). Electroconvulsive therapy was generally safe with subjective memory complaints (85%), headache (69%), and prolonged seizure (8%) as the reported adverse effects possibly related to ECT. Four subjects (6%) developed a manic switch during ECT. Electroconvulsive therapy is an effective and a safe treatment option in adolescent patients with severe and resistant psychopathology. Although comorbidity may decrease treatment response, ECT seems to be effective even in the presence of multiple psychiatric diagnoses.

Identifiants

pubmed: 31094872
doi: 10.1097/YCT.0000000000000602
pii: 00124509-202003000-00011
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

54-59

Références

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Auteurs

Ali Karayağmurlu (A)

From the Department of Child and Adolescent Psychiatry, Faculty of Medicine, Istanbul University, İstanbul.

Murat Coşkun (M)

From the Department of Child and Adolescent Psychiatry, Faculty of Medicine, Istanbul University, İstanbul.

Gülçin Elboğa (G)

Department of Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.

Neera Ghaziuddin (N)

Department of Psychiatry, University of Michigan, Ann Arbor, MI.

Elif Karayağmurlu (E)

Department of Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.

Cem Gökçen (C)

Department of Child and Adolescent Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.

Abdurrahman Altindağ (A)

Department of Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.

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