Predicting skin permeability using the 3D-RISM-KH theory based solvation energy descriptors for a diverse class of compounds.


Journal

Journal of computer-aided molecular design
ISSN: 1573-4951
Titre abrégé: J Comput Aided Mol Des
Pays: Netherlands
ID NLM: 8710425

Informations de publication

Date de publication:
06 2019
Historique:
received: 03 03 2019
accepted: 04 05 2019
pubmed: 16 5 2019
medline: 21 7 2020
entrez: 16 5 2019
Statut: ppublish

Résumé

The state-of-the-art molecular solvation theory is used to predict skin permeability of a large set of compounds with available experimental skin permeability coefficient (logK

Identifiants

pubmed: 31087228
doi: 10.1007/s10822-019-00205-z
pii: 10.1007/s10822-019-00205-z
doi:

Substances chimiques

Organic Chemicals 0
Pharmaceutical Preparations 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

605-611

Références

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Auteurs

Vijaya Kumar Hinge (VK)

Department of Mechanical Engineering, 10-203 Donadeo Innovation Centre for Engineering, University of Alberta, 9211-116 Street NW, Edmonton, AB, T6G 1H9, Canada.
Nanotechnology Research Centre, 11421 Saskatchewan Drive, Edmonton, AB, T6G 2M9, Canada.

Dipankar Roy (D)

Department of Mechanical Engineering, 10-203 Donadeo Innovation Centre for Engineering, University of Alberta, 9211-116 Street NW, Edmonton, AB, T6G 1H9, Canada.
Nanotechnology Research Centre, 11421 Saskatchewan Drive, Edmonton, AB, T6G 2M9, Canada.

Andriy Kovalenko (A)

Department of Mechanical Engineering, 10-203 Donadeo Innovation Centre for Engineering, University of Alberta, 9211-116 Street NW, Edmonton, AB, T6G 1H9, Canada. andriy.kovalenko@ualberta.ca.
Nanotechnology Research Centre, 11421 Saskatchewan Drive, Edmonton, AB, T6G 2M9, Canada. andriy.kovalenko@ualberta.ca.

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Classifications MeSH