A case of zolpidem dependence with extremely high daily doses.
Clonazepam
/ therapeutic use
GABA Modulators
/ therapeutic use
Humans
Hypnotics and Sedatives
/ adverse effects
Irritable Mood
/ drug effects
Male
Middle Aged
Sleep Initiation and Maintenance Disorders
/ chemically induced
Substance Withdrawal Syndrome
/ drug therapy
Substance-Related Disorders
/ diagnosis
Zolpidem
/ adverse effects
dependence
hypnotic
z drug
zolpidem
Journal
Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists
ISSN: 1758-5872
Titre abrégé: Asia Pac Psychiatry
Pays: Australia
ID NLM: 101506757
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
26
01
2019
revised:
19
03
2019
accepted:
25
03
2019
pubmed:
3
5
2019
medline:
9
4
2020
entrez:
3
5
2019
Statut:
ppublish
Résumé
The human population has been witnessing an increase in the number of diseases which are a consequence of progressively increasing physical and mental stress. Insomnia is one such condition whose prevalence is rising all over the world. Apart from the conventional behavioral interventions and use of benzodiazepines, the use of non-benzodiazepine drugs has seen a surge in recent times. The various adverse effects associated with benzodiazepines, dependence potential being one of them, led to an ever increasing use of non-benzodiazepine sedatives like zolpidem and zopiclone all over the world. But with their continuous and ever increasing use, it is seen that even these drugs carry dependence potential. Numerous cases of zolpidem abuse have been reported in literature until now. Here, we are presenting the case of a zolpidem-dependent patient who consumed it in quantities of 2400 mg/day, a quantity not reported anywhere in literature and around 240 times more than its usual prescribed daily dosage.
Substances chimiques
GABA Modulators
0
Hypnotics and Sedatives
0
Clonazepam
5PE9FDE8GB
Zolpidem
7K383OQI23
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12356Informations de copyright
© 2019 John Wiley & Sons Australia, Ltd.
Références
Aragona, M. J. C. n. (2000). Abuse, Dependence, and Epileptic Seizures after Zolpidem Withdrawal [colon] Review and Case Report. Clinical Neuropharmacology, 23(5), 281-283.
Chattopadhyay, A. C., Shukla, L., Kandasamy, A., & Benegal, V. (2016). High-dose zolpidem dependence-Psychostimulant effects? A case report and literature review. Industrial Psychiatry Journal, 25(2), 222.
Cubała, W. J., Landowski, J., & Wichowicz, H. M. (2008). Zolpidem abuse, dependence and withdrawal syndrome: sex as susceptibility factor for adverse effects. British Journal of Clinical Pharmacology, 65(3), 444-445.
Harrison, T. S., & Keating, G. M. J. C. d. (2005). Zolpidem. CNS Drugs, 19(1), 65-89.
Holm, K. J., & Goa, K. L. J. D. (2000). Zolpidem. Drugs, 59(4), 865-889.
Liappas, I., Malitas, P. N., Dimopoulos, N. P., Gitsa, O. E., Liappas, A. I., Nikolaou, C. K., & Christodoulou, G. N. (2003). Zolpidem dependence case series: possible neurobiological mechanisms and clinical management. Journal of Psychopharmacology, 17(1), 131-135.
Lichtenwalner, M., & Tully, R. J. J. o. a. t. (1997). A fatality involving zolpidem. Journal of Analytical Toxicology, 21(7), 567-569.
Morinan, A., & Keaney, F. J. J. o. m. c. r. (2010). Long-term misuse of zopiclone in an alcohol dependent woman with a history of anorexia nervosa: a case report. Journal of Medical Case Reports, 4(1), 403.
Pourshams, M., & Malakouti, S. K. J. D. J. o. P. S. (2014). Zolpidem abuse and dependency in an elderly patient with major depressive disorder: a case report. DARU Journal of Pharmaceutical Sciences, 22(1), 54.
Victorri-Vigneau, C., Dailly, E., Veyrac, G., & Jolliet, P. (2007). Evidence of zolpidem abuse and dependence: results of the French Centre for Evaluation and Information on Pharmacodependence (CEIP) network survey. British Journal of Clinical Pharmacology, 64(2), 198-209.
Victorri-Vigneau, C., Gerardin, M., Rousselet, M., Guerlais, M., Grall-Bronnec, M., & Jolliet, P. (2014). An update on zolpidem abuse and dependence. Journal of Addictive Diseases, 33(1), 15-23.
Yen, C. F., Ko, C. H., Chang, Y. P., Yu, C. Y., Huang, M. F., Yeh, Y. C., … Chen, C. S. (2015). Dependence, misuse, and beliefs regarding use of hypnotics by elderly psychiatric patients taking zolpidem, estazolam, or flunitrazepam. Asia-Pacific Psychiatry, 7(3), 298-305.