Predictors of Transition to Psychosis in Individuals at Clinical High Risk.
Clinical high risk
Prodrome
Psychosis
Risk factors
Schizophrenia, predictors
Journal
Current psychiatry reports
ISSN: 1535-1645
Titre abrégé: Curr Psychiatry Rep
Pays: United States
ID NLM: 100888960
Informations de publication
Date de publication:
29 04 2019
29 04 2019
Historique:
entrez:
1
5
2019
pubmed:
1
5
2019
medline:
23
2
2020
Statut:
epublish
Résumé
Current research is examining predictors of the transition to psychosis in youth who are at clinical high risk based on attenuated psychotic symptoms (APS). Determining predictors of the development of psychosis is important for an improved understanding of mechanisms as well as the development of preventative strategies. The purpose is to review the most recent literature identifying predictors of the transition to psychosis in those who are already assessed as being at risk. Multidomain models, in particular, integrated models of symptoms, social functioning, and cognition variables, achieve better predictive performance than individual factors. There are many methodological issues; however, several solutions have now been described in the literature. For youth who already have APS, predicting who may go on to later develop psychosis is possible. Several studies are underway in large consortiums that may overcome some of the methodological concerns and develop improved means of prediction.
Identifiants
pubmed: 31037392
doi: 10.1007/s11920-019-1027-y
pii: 10.1007/s11920-019-1027-y
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
39Subventions
Organisme : CIHR
Pays : Canada
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