Primary Clear Cell Carcinoma with no Diethylstilbestrol Exposure; Case Series.
Cervix uteri
Diethylstilbestrol
Vagina
Clear cell adenocarcinoma
Journal
Iranian journal of medical sciences
ISSN: 0253-0716
Titre abrégé: Iran J Med Sci
Pays: Iran
ID NLM: 8104374
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
entrez:
3
4
2019
pubmed:
3
4
2019
medline:
3
4
2019
Statut:
ppublish
Résumé
One of the rare neoplasms of cervix uteri and vagina is clear cell carcinoma; mostly in patients with a positive past medical history of intrauterine diethylstilbestrol (DES) exposure which reveals the importance of other unknown risk factors of gynecologic neoplasms. 2 Asian women referred to the gynecology-oncology department. The first one came with a complaint of prolonged vaginal discharge and the second one with irregular bleeding. Neither did report a history of DES-exposure. On vaginal examination, it was found that both cases had mass which biopsied for histologic study. They were diagnosed with primary Clear Cell Carcinoma of Vagina in the first case and Cervix uteri in the other one. Both patients underwent cytoreductive surgery soon after diagnosis.
Types de publication
Case Reports
Langues
eng
Pagination
163-167Déclaration de conflit d'intérêts
Conflict of Interest: None declared.
Références
Gynecol Oncol. 2008 Jun;109(3):335-9
pubmed: 18394687
Int J Gynecol Cancer. 2011 Jan;21(1):137-40
pubmed: 21178575
Int J Gynecol Pathol. 2012 May;31(3):294-6
pubmed: 22498949
Onco Targets Ther. 2014 Jan 09;7:111-6
pubmed: 24470762
Iran J Med Sci. 2014 May;39(3):298-303
pubmed: 24850989
J Clin Diagn Res. 2014 Aug;8(8):OD01-2
pubmed: 25302238
Gynecol Oncol Rep. 2017 Feb 22;20:34-36
pubmed: 28275694