Structure⁻Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues.

Anti-Bacterial Agents / chemistry Antimicrobial Cationic Peptides / chemistry Circular Dichroism Dose-Response Relationship, Drug Methicillin-Resistant Staphylococcus aureus / drug effects Microbial Sensitivity Tests Molecular Structure Myelin Basic Protein / chemistry Peptide Fragments / chemistry Structure-Activity Relationship
Pseudomonas aeruginosa antimicrobial canine infections methicillin-resistant Staphylococcus pseudintermedius mode of action peptide peptoid

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
21 Mar 2019
Historique:
received: 18 02 2019
revised: 12 03 2019
accepted: 12 03 2019
entrez: 24 3 2019
pubmed: 25 3 2019
medline: 16 7 2019
Statut: epublish

Résumé

Methicillin-resistant

Identifiants

DOI: 10.3390/molecules24061121 PMID: 30901860 PMC: PMC6470533
pubmed: 30901860
pii: molecules24061121
doi: 10.3390/molecules24061121
pmc: PMC6470533
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Antimicrobial Cationic Peptides 0
Myelin Basic Protein 0
Peptide Fragments 0
peptide L 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Augustinus Foundation, Bdr. Hartmanns Foundation and Hørslev Foundation
ID : NA
Organisme : FP7 People: Marie-Curie Actions
ID : 289285

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Auteurs

Ines Greco (I)

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. ines.greco@food.ku.dk.
ORCID: 0000-0002-2348-3688

Johannes E Hansen (JE)

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. johanneselton@hotmail.com.

Bimal Jana (B)

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Denmark. bimal@sund.ku.dk.

Natalia Molchanova (N)

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. natalia.molchanova@sund.ku.dk.
ORCID: 0000-0001-7643-4508

Alberto Oddo (A)

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. albi.oddo@gmail.com.

Peter W Thulstrup (PW)

Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark. pwt@chem.ku.dk.
ORCID: 0000-0002-9241-4352

Peter Damborg (P)

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Denmark. pedam@sund.ku.dk.
ORCID: 0000-0001-9932-5996

Luca Guardabassi (L)

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Stigbøjlen 4, 1870 Frederiksberg C, Denmark. lg@sund.ku.dk.
Department of Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK. lg@sund.ku.dk.

Paul R Hansen (PR)

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. prh@sund.ku.dk.
ORCID: 0000-0001-9357-8001

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Classifications MeSH

Recherchemedicale.com › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Phénomènes chimiques › Structure moléculaire › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines de la myéline › Protéine basique de la myéline › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Acides aminés, peptides et protéines › Peptides › Fragments peptidiques › Structure⁻Activity Study, Characterization,...
Recherchemedicale.com › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Structure⁻Activity Study, Characterization,...