A Metal-Free DOTA-Conjugated

Animals Chelating Agents / chemistry Fluorine Radioisotopes / chemistry Heterocyclic Compounds, 1-Ring / chemistry Kidney / metabolism Melanoma, Experimental / diagnostic imaging Mice Mice, Inbred C57BL Positron-Emission Tomography / methods Radiopharmaceuticals / chemistry

Journal

Bioconjugate chemistry
ISSN: 1520-4812
Titre abrégé: Bioconjug Chem
Pays: United States
ID NLM: 9010319

Informations de publication

Date de publication:
17 04 2019
Historique:
pubmed: 22 3 2019
medline: 18 2 2020
entrez: 22 3 2019
Statut: ppublish

Résumé

DOTA is commonly used for radiometal chelation in molecular imaging. Yet in the absence of a radiometal, DOTA is hypothesized to promote renal clearance of

Identifiants

DOI: 10.1021/acs.bioconjchem.9b00146 PMID: 30896929
pubmed: 30896929
doi: 10.1021/acs.bioconjchem.9b00146
doi:

Substances chimiques

Chelating Agents 0
Fluorine Radioisotopes 0
Heterocyclic Compounds, 1-Ring 0
Radiopharmaceuticals 0
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid 1HTE449DGZ
Fluorine-18 GZ5I74KB8G

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1210-1219

Auteurs

Áron Roxin (Á)

Chemistry Department , University of British Columbia , 2036 Main Mall , Vancouver , British Columbia V6T 1Z1 , Canada.

Chengcheng Zhang (C)

Molecular Oncology , British Columbia Cancer Agency Research Centre , 675 West 10th Avenue , Vancouver , British Columbia V5Z 1L3 , Canada.
ORCID: 0000-0001-5786-4748

Sungjoon Huh (S)

Chemistry Department , University of British Columbia , 2036 Main Mall , Vancouver , British Columbia V6T 1Z1 , Canada.

Mathieu Lepage (M)

Chemistry Department , University of British Columbia , 2036 Main Mall , Vancouver , British Columbia V6T 1Z1 , Canada.
ORCID: 0000-0001-5236-7902

Zhengxing Zhang (Z)

Molecular Oncology , British Columbia Cancer Agency Research Centre , 675 West 10th Avenue , Vancouver , British Columbia V5Z 1L3 , Canada.

Kuo-Shyan Lin (KS)

Molecular Oncology , British Columbia Cancer Agency Research Centre , 675 West 10th Avenue , Vancouver , British Columbia V5Z 1L3 , Canada.
ORCID: 0000-0002-0739-0780

François Bénard (F)

Molecular Oncology , British Columbia Cancer Agency Research Centre , 675 West 10th Avenue , Vancouver , British Columbia V5Z 1L3 , Canada.

David M Perrin (DM)

Chemistry Department , University of British Columbia , 2036 Main Mall , Vancouver , British Columbia V6T 1Z1 , Canada.
ORCID: 0000-0001-8342-6346

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Classifications MeSH

Recherchemedicale.com › Eucaryotes › Animaux › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents séquestrants › Chélateurs › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Radio-isotopes du fluor › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Composés hétérocycliques › Composés hétéromonocycliques › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Appareil urogénital › Voies urinaires › Rein › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Techniques d'investigation › Modèles animaux › Tumeurs expérimentales › Mélanome expérimental › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › A Metal-Free DOTA-Conjugated
Recherchemedicale.com › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Radiopharmaceutiques › A Metal-Free DOTA-Conjugated