Knee Joint Distraction Compared with High Tibial Osteotomy and Total Knee Arthroplasty: Two-Year Clinical, Radiographic, and Biochemical Marker Outcomes of Two Randomized Controlled Trials.
Adult
Arthroplasty, Replacement, Knee
/ statistics & numerical data
Biomarkers
/ analysis
Collagen Type II
/ metabolism
Equivalence Trials as Topic
Female
Follow-Up Studies
Humans
Hyaline Cartilage
/ pathology
Knee Joint
/ metabolism
Male
Middle Aged
Minimal Clinically Important Difference
Osteoarthritis, Knee
/ pathology
Osteotomy
/ methods
Radiography
/ methods
Randomized Controlled Trials as Topic
Tibia
/ metabolism
Treatment Outcome
distraction
joint-preserving surgery
knee joint distraction (KJD)
randomized controlled trial (RCT)
Journal
Cartilage
ISSN: 1947-6043
Titre abrégé: Cartilage
Pays: United States
ID NLM: 101518378
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
pubmed:
14
2
2019
medline:
30
10
2021
entrez:
14
2
2019
Statut:
ppublish
Résumé
Both, knee joint distraction (KJD) and high tibial osteotomy (HTO) are joint-preserving surgeries that postpone total knee arthroplasty (TKA) in younger osteoarthritis (OA) patients. Here we evaluate the 2-year follow-up of KJD versus TKA and KJD versus HTO in 2 noninferiority studies. Knee OA patients indicated for TKA were randomized to KJD ( Both trials were completed, with 114 patients (19 KJD Sustained improvement of clinical benefit and (hyaline) cartilage thickness increase after KJD is demonstrated. KJD was clinically noninferior to HTO and TKA in the primary outcome.
Identifiants
pubmed: 30758214
doi: 10.1177/1947603519828432
pmc: PMC7970375
doi:
Substances chimiques
Biomarkers
0
Collagen Type II
0
Banques de données
NTR
['NTR2809', 'NTR2900']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
181-191Commentaires et corrections
Type : ErratumIn
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