Compliance with ethical standards in the reporting of donor sources and ethics review in peer-reviewed publications involving organ transplantation in China: a scoping review.
china
executed prisoners
organ donation
publication ethics
scoping review
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
05 02 2019
05 02 2019
Historique:
entrez:
7
2
2019
pubmed:
7
2
2019
medline:
23
2
2020
Statut:
epublish
Résumé
The objective of this study is to investigate whether papers reporting research on Chinese transplant recipients comply with international professional standards aimed at excluding publication of research that: (1) involves any biological material from executed prisoners; (2) lacks Institutional Review Board (IRB) approval and (3) lacks consent of donors. Scoping review based on Arksey and O'Mallee's methodological framework. Medline, Scopus and Embase were searched from January 2000 to April 2017. We included research papers published in peer-reviewed English-language journals reporting on outcomes of research involving recipients of transplanted hearts, livers or lungs in mainland China. Data were extracted by individual authors working independently following training and benchmarking. Descriptive statistics were compiled using Excel. 445 included studies reported on outcomes of 85 477 transplants. 412 (92.5%) failed to report whether or not organs were sourced from executed prisoners; and 439 (99%) failed to report that organ sources gave consent for transplantation. In contrast, 324 (73%) reported approval from an IRB. Of the papers claiming that no prisoners' organs were involved in the transplants, 19 of them involved 2688 transplants that took place prior to 2010, when there was no volunteer donor programme in China. The transplant research community has failed to implement ethical standards banning publication of research using material from executed prisoners. As a result, a large body of unethical research now exists, raising issues of complicity and moral hazard to the extent that the transplant community uses and benefits from the results of this research. We call for retraction of this literature pending investigation of individual papers.
Identifiants
pubmed: 30723071
pii: bmjopen-2018-024473
doi: 10.1136/bmjopen-2018-024473
pmc: PMC6377532
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e024473Commentaires et corrections
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: Dr AB is a member of the New Zealand Advocacy & Initiatives Committee (NZAIC) of the International Coalition to End Transplant Abuse in China, Dr BB has nothing to disclose, Dr RC has nothing to disclose, Dr RC-W is a member of the Australian Advocacy and Initiatives Committee of the International Coalition to End Transplant Abuse in China, Professor MFS is a member of the Ethics Committee of Doctors Against Forced Organ Harvesting, and a member of the Australian Advocacy and Initiatives Committee of the International Coalition to End Transplant Abuse in China, MPR reports that he is an occasional expert contributor to the International Coalition to End Transplant Abuse in China, Professor WR is a Director of the NGO ’International Coalition to End Transplant Abuse in China' and is chair of its International Advisory Committee.
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