The impact of lifestyle factors on evolution of atopic dermatitis: An alternative approach.

atopic dermatitis diet lifestyle microbioma neuroendocrine factors psychoneuroimmunology stress

Journal

Experimental and therapeutic medicine
ISSN: 1792-0981
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 13 08 2018
accepted: 26 09 2018
entrez: 26 1 2019
pubmed: 27 1 2019
medline: 27 1 2019
Statut: ppublish

Résumé

Atopic dermatitis (AD) is a multifactorial chronic inflammatory disease with an incompletely understood etiopathogenesis. With a significant impact on the quality of life of patients, AD has attracted the interest of many research studies aiming to investigate the complex cellular and molecular mechanisms and to identify new therapeutic pathways. Various studies have focused on psycho-immunology, emphasizing the involvement of stress, defined as a general response of the body to external or internal challenges to the AD pathology. Factors like lifestyle and leisure activities may change the behavior of immune cells in AD with a strong impact on the evolution of the disease. Moreover, the poor adherence of AD patient to standard treatment approach has led to the necessity to combine different therapies in the field of complementary and alternative medicine. Although there are still not enough data to conclude that adjuvant therapies are effective in a conventional sense, there are already promising results suggesting that alternative therapeutic strategies could be a main subject of further research.

Identifiants

pubmed: 30679977
doi: 10.3892/etm.2018.6980
pii: ETM-0-0-6980
pmc: PMC6327646
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1078-1084

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Auteurs

Iulia Solomon (I)

Department of Dermatology and Allergology, Elias Emergency University Hospital, 011461 Bucharest, Romania.

Mihaela Adriana Ilie (MA)

Dermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Biochemistry, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Carmen Draghici (C)

Department of Dermatology and Allergology, Elias Emergency University Hospital, 011461 Bucharest, Romania.

Vlad Mihai Voiculescu (VM)

Department of Dermatology and Allergology, Elias Emergency University Hospital, 011461 Bucharest, Romania.
Dermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Constantin Căruntu (C)

Department of Physiology, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Dermatology, 'Prof. N. Paulescu' National Institute of Diabetes, Nutrition and Metabolic Diseases, 011233 Bucharest, Romania.

Daniel Boda (D)

Dermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Dermatology, 'Prof. N. Paulescu' National Institute of Diabetes, Nutrition and Metabolic Diseases, 011233 Bucharest, Romania.

Sabina Zurac (S)

Department of Pathology, Faculty of Dental Medicine, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Pathology, Colentina Clinical Hospital, 020125 Bucharest, Romania.

Classifications MeSH