Risk factors for loss of skeletal muscle mass in patients with cirrhosis.
WFA+-M2BP
liver cirrhosis
liver fibrosis
malnutrition
skeletal muscle
Journal
Hepatology research : the official journal of the Japan Society of Hepatology
ISSN: 1386-6346
Titre abrégé: Hepatol Res
Pays: Netherlands
ID NLM: 9711801
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
13
10
2018
revised:
11
12
2018
accepted:
31
12
2018
pubmed:
10
1
2019
medline:
10
1
2019
entrez:
10
1
2019
Statut:
ppublish
Résumé
The present study aimed to assess the correlation between loss of skeletal muscle mass (LSMM) and the clinical characteristics of patients with liver cirrhosis. This multicenter, prospective study was undertaken at five locations in Japan and involved a 12-month observation period. After baseline assessment, the change in the skeletal muscle index per year (ΔSMI/y) was evaluated in the enrolled patients; LSMM was defined as ΔSMI/y < 0. We evaluated the relationships between LSMM and baseline clinical characteristics in patients with liver cirrhosis. A total of 166 patients with cirrhosis were enrolled and, of these, 123 patients (74.1%) showed LSMM. Multivariate analysis confirmed that hepatic encephalopathy, Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA Advanced age, low grip strength, hepatic encephalopathy, and high WFA
Types de publication
Journal Article
Langues
eng
Pagination
550-558Informations de copyright
© 2019 The Japan Society of Hepatology.