A New Insight on Activation of Human Endogenous Retroviruses (HERVs) in Malignant Melanoma upon Exposure to CuSO4.
Cell cytotoxicity
CuSO4
Human endogenous retrovirus (HERVs)
Malignant melanoma
Journal
Biological trace element research
ISSN: 1559-0720
Titre abrégé: Biol Trace Elem Res
Pays: United States
ID NLM: 7911509
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
15
10
2018
accepted:
05
12
2018
pubmed:
13
12
2018
medline:
25
12
2019
entrez:
13
12
2018
Statut:
ppublish
Résumé
Human endogenous retroviruses (HERVs) are semi-conserved subtypes of long-terminal repeats containing retrotransposons that constitute approximately 8% of the genome. Under pathological conditions, the expression of HERVs is also affected by epigenetic modifications. The extent to which the activation of human endogenous retroviruses can be influenced upon exposure to copper remains to be evaluated. Thus, the present study was designed to evaluate the effects of CuSO
Identifiants
pubmed: 30539386
doi: 10.1007/s12011-018-1605-6
pii: 10.1007/s12011-018-1605-6
doi:
Substances chimiques
RNA, Messenger
0
RNA, Neoplasm
0
RNA, Viral
0
Copper Sulfate
LRX7AJ16DT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
70-74Subventions
Organisme : Tabriz University of Medical Sciences
ID : 58853